Omeprazole
- Generic Name
- Omeprazole
- Brand Names
- Konvomep, Losec, Omeclamox, Omesec, Previdolrx Analgesic Pak, Prilosec, Talicia, Yosprala, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 73590-58-6
- Unique Ingredient Identifier
- KG60484QX9
- Background
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approva...
- Indication
Omeprazole, according to the FDA label is a proton pump inhibitor (PPI) used for the following purposes:
• Treatment of active duodenal ulcer in adults
• Eradication of Helicobacter pylori to reduce the risk of duodenal ulcer
recurrence in adults
• Treatment of active benign gastric ulcer in adults
...
- Associated Conditions
- Ankylosing Spondylitis (AS), Duodenal Ulcer, Erosive Esophagitis, Gastric Ulcer, Gastro-esophageal Reflux Disease (GERD), Healing, Heartburn, Helicobacter Pylori Infection, Osteoarthritis (OA), Rheumatoid Arthritis, Upper GI Bleeding, Zollinger-Ellison Syndrome, Benign, active Gastric Ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Multiple endocrine adenomas
- Associated Therapies
- -
Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features
- Conditions
- Interventions
- First Posted Date
- 2019-07-22
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- St. Luke's Medical Center, Philippines
- Target Recruit Count
- 82
- Registration Number
- NCT04028466
- Locations
- 🇵🇭
St. Luke's Medical Center, Quezon City, National Capital Region, Philippines
Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal Bleeding
- First Posted Date
- 2019-06-10
- Last Posted Date
- 2019-06-10
- Lead Sponsor
- Medical University of Bialystok
- Target Recruit Count
- 50
- Registration Number
- NCT03980496
- Locations
- 🇵🇱
Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, Białystok, Podlaskie, Poland
A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy Participants
- First Posted Date
- 2019-05-03
- Last Posted Date
- 2019-09-23
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 16
- Registration Number
- NCT03936374
- Locations
- 🇺🇸
PPD Phase I Clinic, Austin, Texas, United States
Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of SPD422 (Anagrelide Hydrochloride) in Healthy Adult Participants
- First Posted Date
- 2019-03-07
- Last Posted Date
- 2021-06-15
- Lead Sponsor
- Shire
- Target Recruit Count
- 20
- Registration Number
- NCT03866434
- Locations
- 🇺🇸
New Orleans Center for Clinical Research, Knoxville, Tennessee, United States
Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
- First Posted Date
- 2019-03-06
- Last Posted Date
- 2023-06-08
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 56
- Registration Number
- NCT03864042
- Locations
- 🇨🇦
Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
🇺🇸UC Irvine Health, Orange, California, United States
🇺🇸University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora, Colorado, United States
Evaluation of GERDOFF Efficacy in Combination With Proton Pump Inhibitor
- Conditions
- Interventions
- First Posted Date
- 2019-01-04
- Last Posted Date
- 2020-03-31
- Lead Sponsor
- SOFAR S.p.A.
- Target Recruit Count
- 72
- Registration Number
- NCT03793556
- Locations
- 🇮🇹
dr Alessandro Repici, Rozzano, MI, Italy
EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone
- First Posted Date
- 2018-12-20
- Last Posted Date
- 2018-12-20
- Lead Sponsor
- Claire Daniels
- Target Recruit Count
- 100
- Registration Number
- NCT03781596
- Locations
- 🇺🇸
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Drug Interaction Study of CT1812 in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2018-10-23
- Last Posted Date
- 2018-10-23
- Lead Sponsor
- Cognition Therapeutics
- Target Recruit Count
- 16
- Registration Number
- NCT03716427
- Locations
- 🇺🇸
Jasper Clinic, Kalamazoo, Michigan, United States
Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs
- Conditions
- Interventions
- First Posted Date
- 2018-10-17
- Last Posted Date
- 2022-01-26
- Lead Sponsor
- Viriom
- Target Recruit Count
- 56
- Registration Number
- NCT03709355
- Locations
- 🇷🇺
Central Clinical City Hospital, Reutov, Moscow Region, Russian Federation
Indomethacin for Refractory Chronic Cough
- Conditions
- Interventions
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2018-11-26
- Target Recruit Count
- 84
- Registration Number
- NCT03662269
- Locations
- 🇨🇳
The First Affiliated Hospital Of Guangzhou Medical University, Guangzhou, Guangdong, China
Drug Development Updates
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