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LOXO ONCOLOGY, INC.

LOXO ONCOLOGY, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
2013-01-01
Employees
1K
Market Cap
-
Website
http://www.loxooncology.com

Clinical Trials

23

Active:13
Completed:7

Trial Phases

3 Phases

Phase 1:8
Phase 2:2
Phase 3:6

Drug Approvals

1

FDA:1

Drug Approvals

VITRAKVI

Approval Date
Dec 5, 2018
FDA

Clinical Trials

Distribution across different clinical trial phases (16 trials with phase data)• Click on a phase to view related trials

Phase 1
8 (50.0%)
Phase 3
6 (37.5%)
Phase 2
2 (12.5%)

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Phase 2
Recruiting
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-07-22
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
249
Registration Number
NCT06588478
Locations
🇺🇸

Ironwood Cancer & Research Centers, Chandler, Arizona, United States

🇺🇸

City of Hope National Medical Center, Irvine, California, United States

🇺🇸

Palo Alto Medical Foundation Research Institute (PAMFRI), Palo Alto, California, United States

and more 132 locations

A Study of Pirtobrutinib (LY3527727 [LOXO-305]) Versus Placebo in Participants With Relapsing Multiple Sclerosis

Phase 2
Withdrawn
Conditions
Relapsing Multiple Sclerosis
Multiple Sclerosis
Interventions
Drug: Placebo
First Posted Date
2023-10-27
Last Posted Date
2024-03-27
Lead Sponsor
Loxo Oncology, Inc.
Registration Number
NCT06104683
Locations
🇺🇸

University of South Florida, Tampa, Florida, United States

🇺🇸

Clinical Trial Network, Houston, Texas, United States

🇺🇸

Swedish Medical Center-501 E Hampden Ave, Seattle, Washington, United States

and more 1 locations

A Study of the Effect of Food on Selpercatinib (LY3527723) in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-04-12
Last Posted Date
2025-03-21
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
46
Registration Number
NCT05324124
Locations
🇸🇬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Phase 3
Active, not recruiting
Conditions
Chronic Lymphocytic Leukemia
Leukemia, B-cell
Leukemia, Lymphocytic
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2022-02-24
Last Posted Date
2025-07-31
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
662
Registration Number
NCT05254743
Locations
🇺🇸

Genesis Cancer Center, Hot Springs, Arkansas, United States

🇺🇸

Pacific Cancer Medical Center, Inc, Anaheim, California, United States

🇺🇸

Alta Bates Summit Medical Center, Berkeley, California, United States

and more 173 locations

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-01-04
Last Posted Date
2022-04-15
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
34
Registration Number
NCT05176314
Locations
🇺🇸

QPS Bio-Kinetic Clinical Applications, Springfield, Missouri, United States

🇺🇸

Covance Dallas, Dallas, Texas, United States

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