MedPath

Calcium

Generic Name
Calcium
Drug Type
Small Molecule
Chemical Formula
Ca
CAS Number
7440-70-2
Unique Ingredient Identifier
SY7Q814VUP
Background

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.

Indication

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.

Associated Conditions
Calcium Deficiency, Deficiency, Vitamin D, Osteodystrophy, Osteomalacia, Osteoporosis, Chronic Hypocalcemia, Chronic Hypocalcemia caused by anticonvulsant medications
Associated Therapies
Care of the Joint, Mineral supplementation therapy, Nutritional supplementation

Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human Myometrium

Not Applicable
Recruiting
Conditions
Postpartum Hemorrhage (Primary)
Interventions
First Posted Date
2025-04-16
Last Posted Date
2025-04-16
Lead Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Target Recruit Count
40
Registration Number
NCT06930391
Locations
🇨🇦

Mount Sinai Hospital, Toronto, Ontario, Canada

To Measure Post Operative Pain Severity by Using Two Different Intra Canal Medicaments Calcium Hydroxide and Triple Antibiotic Paste in Teeth with Single Roots and Periapical Disease Called Apical Periodontitis

Phase 2
Not yet recruiting
Conditions
Apical Periodontitis
Irreversible Pulpitis with Apical Periodontitis
Interventions
Drug: triple antibiotic paste (TAP)
First Posted Date
2025-02-12
Last Posted Date
2025-02-12
Lead Sponsor
Komal Ashraf Khan
Target Recruit Count
180
Registration Number
NCT06821763
Locations
🇵🇰

Margalla Institute Of Health Sciences Quaid e Azam Avenue, Gulraiz phase 3, Gulraiz housing scheme Rawalpindi, Rawalpindi, Punjab, Pakistan

COMPARISON of MINERAL TRIOXIDE AGGREGATE and CALCIUM HYDROXIDE AS INDIRECT PULP CAPPING AGENTS in PRIMARY MOLARS

Phase 4
Completed
Conditions
Indirect Pulp Cap
Interventions
First Posted Date
2025-02-04
Last Posted Date
2025-02-04
Lead Sponsor
Shaheed Zulfiqar Ali Bhutto Medical University
Target Recruit Count
40
Registration Number
NCT06807320
Locations
🇵🇰

Pakistan Institute of Medical Sciences, Islamabad, Capital, Pakistan

Effect of Calcium Silicate-Based Root Canal Medicament After Retreatment

Not Applicable
Completed
Conditions
Antibacterial Agents
Postoperative Dental Pain
Antifungal Agents
Interventions
First Posted Date
2025-01-16
Last Posted Date
2025-01-16
Lead Sponsor
Ataturk University
Target Recruit Count
60
Registration Number
NCT06779370
Locations
🇹🇷

Ataturk University, Erzurum, Turkey

Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding

Not Applicable
Not yet recruiting
Conditions
Menorrhagia
Abnormal Uterine Bleeding
Interventions
First Posted Date
2025-01-08
Last Posted Date
2025-01-08
Lead Sponsor
University of Health Sciences Lahore
Target Recruit Count
100
Registration Number
NCT06763094

Garlic Oil As Root Filling Material in Primary Molars

Not Applicable
Not yet recruiting
Conditions
Irreversible Pulpitis (toothache)
Interventions
Combination Product: Garlic oil
First Posted Date
2025-01-01
Last Posted Date
2025-03-20
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT06755502

Effect of Tranexamic Acid and Calcium Dobesilate for Bleeding of Endometrial Origin

Phase 2
Completed
Conditions
Heavy. Mentrual Bleeding
Abormal utèrine Bleeding
Bleeding
Uterine Bleeding
Hypersensitivity Response
GI Disturbance
Agranulocytosis
Bleeding Pattern
Endometrial Bleeding
Endometrial
Interventions
First Posted Date
2024-11-27
Last Posted Date
2024-11-27
Lead Sponsor
District Headquarters Teaching Hospital Sahiwal
Target Recruit Count
100
Registration Number
NCT06707051
Locations
🇵🇰

Sahiwal teaching Hospital Sahiwal, Sahiwal, Punjab, Pakistan

A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With Solid Tumors

First Posted Date
2024-11-25
Last Posted Date
2025-02-27
Lead Sponsor
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Target Recruit Count
876
Registration Number
NCT06703177
Locations
🇨🇳

Sun Yat-Sen university cancer center, Guangzhou, Guangdong, China

Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Teeth

Phase 4
Not yet recruiting
Conditions
Deep Caries
Indirect Pulp Capping
Mineral Trioxide Aggregate (MTA)
Calcium Hydroxide
Biodentine
Patient Reported Outcome Measures
Interventions
First Posted Date
2024-11-12
Last Posted Date
2024-11-12
Lead Sponsor
Cairo University
Target Recruit Count
35
Registration Number
NCT06683833

Effect of Manual Therapy on Low Back Pain in Osteopenic Postmenopausal Women

Not Applicable
Recruiting
Conditions
Low Back Pain
Osteopenia
Interventions
Other: Manual therapy
First Posted Date
2024-11-04
Last Posted Date
2024-11-11
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT06671665
Locations
🇪🇬

Cairo University, Giza, Egypt

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