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Laropiprant

Generic Name
Laropiprant
Drug Type
Small Molecule
Chemical Formula
C21H19ClFNO4S
CAS Number
571170-77-9
Unique Ingredient Identifier
G7N11T8O78
Background

Laropiprant is an ingredient in the EMA-withdrawn product Pelzont.

A Study of Laropiprant (MK-0524) in Participants With Moderate to Severe Erythematotelangiectatic Rosacea (MK-0524-155)

Phase 1
Completed
Conditions
Rosacea
Interventions
Drug: Placebo for Laropiprant
First Posted Date
2011-10-13
Last Posted Date
2015-03-25
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
60
Registration Number
NCT01451619

A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)

Phase 1
Completed
Conditions
Primary Hypercholesterolemia
Mixed Hyperlipidemia
Interventions
First Posted Date
2009-11-11
Last Posted Date
2015-11-01
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
36
Registration Number
NCT01012219

A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)

Phase 1
Completed
Conditions
Hypercholesterolemia
First Posted Date
2008-10-08
Last Posted Date
2019-11-21
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
26
Registration Number
NCT00769132

A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED)

Phase 1
Completed
Conditions
Type 2 Diabetes Mellitus
First Posted Date
2008-02-20
Last Posted Date
2015-09-07
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
26
Registration Number
NCT00618995

MK0524A Phase IIb Study (0524A-011)(COMPLETED)

Phase 2
Completed
Conditions
Flushing
First Posted Date
2007-09-27
Last Posted Date
2015-08-25
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
154
Registration Number
NCT00536237

MK0524 Seasonal Allergic Rhinitis Study (0524-005)(COMPLETED)

Phase 2
Completed
Conditions
Seasonal Allergies
First Posted Date
2007-09-21
Last Posted Date
2015-12-22
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
766
Registration Number
NCT00533208
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