Indomethacin
- Generic Name
- Indomethacin
- Brand Names
- Indocin, Tivorbex
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16ClNO4
- CAS Number
- 53-86-1
- Unique Ingredient Identifier
- XXE1CET956
- Background
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-ace...
- Indication
Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
...
- Associated Conditions
- Acute Gouty Arthritis, Joint Pain, Moderate to Severe Osteoarthritis, Moderate to Severe Rheumatoid Arthritis, Moderate to severe ankylosing spondylitis, Myalgia, Patent Ductus Arteriosus (PDA), Acute Shoulder Pain
- Associated Therapies
- -
7 cm vs. 5 cm Pancreatic Stents for the Prevention of Post-ERCP Pancreatitis in High-risk Patients
- Conditions
- Interventions
- First Posted Date
- 2019-10-30
- Last Posted Date
- 2019-10-30
- Lead Sponsor
- Air Force Military Medical University, China
- Target Recruit Count
- 800
- Registration Number
- NCT04145336
- Locations
- 🇨🇳
Xijing Hospital of Digestive Diseases, Xi'an, Shanxi, China
Study on Indomethacin-responsive Headaches
- Conditions
- First Posted Date
- 2019-05-30
- Last Posted Date
- 2019-05-30
- Lead Sponsor
- Anne Ducros
- Target Recruit Count
- 100
- Registration Number
- NCT03967483
Comparative Effectiveness Between Indomethacin and Pancreatic Stenting in the Prevention of Post ERCP Pancreatitis
- Conditions
- Interventions
- First Posted Date
- 2018-10-22
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 1734
- Registration Number
- NCT03713879
- Locations
- 🇨🇳
Endoscopy centre, Hangzhou, Zhejiang, China
🇨🇳Eastern Hepatobiliary Surgery Hospital,Endoscopy centre, Shanghai, Shanghai, China
🇭🇰Endoscopy Centre, Prince of Wales Hospital, Hong Kong, Hong Kong
Evaluate the Safety, Tolerability, & Pharmacokinetics of K-285 Compared With Indomethacin Capsule in Healthy Adults
- First Posted Date
- 2018-10-19
- Last Posted Date
- 2019-01-17
- Lead Sponsor
- Kowa Research Institute, Inc.
- Target Recruit Count
- 15
- Registration Number
- NCT03712241
- Locations
- 🇺🇸
PPD Development, LP, Austin, Texas, United States
Indomethacin for Refractory Chronic Cough
- Conditions
- Interventions
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2018-11-26
- Target Recruit Count
- 84
- Registration Number
- NCT03662269
- Locations
- 🇨🇳
The First Affiliated Hospital Of Guangzhou Medical University, Guangzhou, Guangdong, China
Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus
- Conditions
- Interventions
- First Posted Date
- 2018-08-27
- Last Posted Date
- 2024-10-18
- Lead Sponsor
- University of Oulu
- Target Recruit Count
- 22
- Registration Number
- NCT03648437
- Locations
- 🇫🇮
Helsinki Univeristy Central Hospital, Helsinki, Finland
🇫🇮Department of Pediatrics, Oulu University Hospital, Oulu, Finland
🇫🇮Tampere University Hospital, Tampere, Finland
The Effect of Dehydration on Intestinal Permeability
- Conditions
- Interventions
- First Posted Date
- 2018-08-08
- Last Posted Date
- 2018-08-08
- Lead Sponsor
- Örebro University, Sweden
- Target Recruit Count
- 20
- Registration Number
- NCT03620825
- Locations
- 🇸🇪
Örebro University, Örebro, Örebro County, Sweden
Acetaminophen vs Indomethacin in Treating hsPDA
- Conditions
- Interventions
- First Posted Date
- 2018-05-25
- Last Posted Date
- 2019-12-03
- Lead Sponsor
- University of Tennessee
- Target Recruit Count
- 37
- Registration Number
- NCT03537144
- Locations
- 🇺🇸
Methodist-Lebonheur Germantown Hospital, Memphis, Tennessee, United States
🇺🇸Regional One Health, Memphis, Tennessee, United States
🇺🇸LeBonheur Children's Hospital, Memphis, Tennessee, United States
Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis
- Conditions
- Interventions
- First Posted Date
- 2018-03-22
- Last Posted Date
- 2020-09-22
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 9
- Registration Number
- NCT03473665
- Locations
- 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States
IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3
- Conditions
- Interventions
- First Posted Date
- 2017-08-30
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 11
- Registration Number
- NCT03267680
- Locations
- 🇺🇸
University of Oklahoma Health Sciences Center, Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
🇺🇸USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Drug Development Updates
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