Indomethacin
- Generic Name
- Indomethacin
- Brand Names
- Indocin, Tivorbex
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16ClNO4
- CAS Number
- 53-86-1
- Unique Ingredient Identifier
- XXE1CET956
- Background
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-ace...
- Indication
Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
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- Associated Conditions
- Acute Gouty Arthritis, Joint Pain, Moderate to Severe Osteoarthritis, Moderate to Severe Rheumatoid Arthritis, Moderate to severe ankylosing spondylitis, Myalgia, Patent Ductus Arteriosus (PDA), Acute Shoulder Pain
- Associated Therapies
- -
Ranibizumab Plus Indomethacin
- First Posted Date
- 2017-08-25
- Last Posted Date
- 2017-08-25
- Lead Sponsor
- Università degli Studi di Brescia
- Target Recruit Count
- 58
- Registration Number
- NCT03261635
Comparison of Nifedipine Versus Indomethacin for Acute Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2017-04-26
- Last Posted Date
- 2021-11-05
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 36
- Registration Number
- NCT03129945
- Locations
- 🇺🇸
University of California, Davis, Sacramento, California, United States
🇺🇸University of California, Irvine, Orange, California, United States
🇺🇸University of California, Los Angeles, Los Angeles, California, United States
Effect of Papillary Epinephrine Spraying on Post-ERCP Pancreatitis in Patients Received Rectal Indomethacin
- Conditions
- Interventions
- First Posted Date
- 2017-02-20
- Last Posted Date
- 2017-10-27
- Lead Sponsor
- Air Force Military Medical University, China
- Target Recruit Count
- 3300
- Registration Number
- NCT03057769
- Locations
- 🇨🇳
Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
🇨🇳Endoscopy Center, Ankang Central Hospital, Ankang, Shaanxi, China
🇨🇳Xijing Hospital of Digestive Diseases, Xi'an, Shaanxi, China
COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis
- First Posted Date
- 2016-11-16
- Last Posted Date
- 2016-11-16
- Target Recruit Count
- 2700
- Registration Number
- NCT02964403
Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)
- Conditions
- Interventions
- First Posted Date
- 2016-11-01
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- Providence Health & Services
- Target Recruit Count
- 16
- Registration Number
- NCT02950259
- Locations
- 🇺🇸
Providence Portland Medical Center, Portland, Oregon, United States
Oral Resveratrol to Prevent Post-ERCP Pancreatitis
- Conditions
- Interventions
- First Posted Date
- 2016-10-28
- Last Posted Date
- 2016-10-28
- Target Recruit Count
- 2700
- Registration Number
- NCT02947932
Enzalutamide and Indomethacin in Treating Patients With Recurrent or Metastatic Hormone-Resistant Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2016-10-17
- Last Posted Date
- 2023-11-29
- Lead Sponsor
- Mamta Parikh
- Target Recruit Count
- 38
- Registration Number
- NCT02935205
- Locations
- 🇺🇸
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Early Treatment Versus Expectative Management of PDA in Preterm Infants
- Conditions
- Interventions
- First Posted Date
- 2016-08-30
- Last Posted Date
- 2023-07-03
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 273
- Registration Number
- NCT02884219
- Locations
- 🇳🇱
Radboudumc Amalia Children's Hospital, Nijmegen, Netherlands
🇧🇪University Hospital Antwerp, Antwerp, Belgium
🇧🇪University Hospital Brussels, Brussels, Belgium
A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy
- Conditions
- Interventions
- First Posted Date
- 2016-07-29
- Last Posted Date
- 2022-01-13
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 22
- Registration Number
- NCT02849990
- Locations
- 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States
A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis
- First Posted Date
- 2016-02-26
- Last Posted Date
- 2021-04-22
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 42
- Registration Number
- NCT02692391
- Locations
- 🇺🇸
Univeristy of Pittsburgh, Pittsburgh, Pennsylvania, United States
Drug Development Updates
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