Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Investigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Mayo Clinic, Rochester, Minnesota, United States
Johns Hopkins University, Baltimore, Maryland, United States
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