Dydrogesterone
- Generic Name
- Dydrogesterone
- Drug Type
- Small Molecule
- Chemical Formula
- C21H28O2
- CAS Number
- 152-62-5
- Unique Ingredient Identifier
- 90I02KLE8K
- Background
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
- Indication
Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history of habitual abortions.
- Associated Conditions
- Infertility, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome (PMS), Recurrent Miscarriages, Spontaneous Abortions
- Associated Therapies
- Assisted Reproductive Technology therapy, Menstrual Regulation
Non-interventional Study of Therapy for Threatened Miscarriage
- Conditions
- Threatened Miscarriage
- Interventions
- First Posted Date
- 2017-10-16
- Last Posted Date
- 2018-01-18
- Lead Sponsor
- Besins Healthcare
- Target Recruit Count
- 1241
- Registration Number
- NCT03309735
- Locations
- 🇷🇺
Regional perinatal center, Kursk, Kursk Region, Russian Federation
🇷🇺City Clinical Hospital of the Demsk District, Ufa, Bashkortostan Republic, Russian Federation
🇷🇺Сity hospital №7, Samara, Samara Region, Russian Federation
Progesterone and Doppler in Recurrent Abortion
- Conditions
- Abortion in First Trimester
- Interventions
- First Posted Date
- 2017-08-30
- Last Posted Date
- 2017-09-08
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 50
- Registration Number
- NCT03267771
- Locations
- 🇪🇬
Gehad Elsherief, Assiut, Egypt
The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss
- Conditions
- Recurrent Pregnancy Loss
- Interventions
- First Posted Date
- 2016-12-13
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Shanghai First Maternity and Infant Hospital
- Target Recruit Count
- 500
- Registration Number
- NCT02990403
- Locations
- 🇨🇳
Shanghai first Maternity and Infant health hospital, Tong Ji University, Shanghai, China
Efficacy of Oral Progesterone and Vaginal Progesterone After Tocolytic Therapy in Threatened Preterm Labor
- Conditions
- Preterm Delivery
- Interventions
- First Posted Date
- 2016-12-12
- Last Posted Date
- 2017-10-10
- Lead Sponsor
- Sanpasitthiprasong Hospital
- Target Recruit Count
- 231
- Registration Number
- NCT02989519
- Locations
- 🇹🇭
Piyawadee Wuttikonsammakit, Nai Muang, Ubon Ratchathani, Thailand
A Survey on Efficacy and Safety in Patients With Endometriosis
- First Posted Date
- 2016-10-03
- Last Posted Date
- 2022-07-06
- Lead Sponsor
- Mylan Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT02921763
- Locations
- 🇯🇵
Mylan Investigational Site A, Kamigyo-ku, Kyoto, Japan
🇯🇵Mylan Investigational Site D, Saitama, Iwatsukiku, Japan
🇯🇵Mylan Investigational Site E, Kyoto, Ukyouku, Japan
Use of Cyclosporin A for the Treatment of Recurrent Miscarriage
- First Posted Date
- 2016-03-11
- Last Posted Date
- 2016-03-15
- Lead Sponsor
- Fudan University
- Target Recruit Count
- 384
- Registration Number
- NCT02706470
- Locations
- 🇨🇳
Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
Fibroids in Women of Reproductive Age and Women Pregnancy
- Conditions
- Fibroids
- Interventions
- First Posted Date
- 2015-12-03
- Last Posted Date
- 2015-12-03
- Lead Sponsor
- Trieu, Nguyen Thi, M.D.
- Target Recruit Count
- 22
- Registration Number
- NCT02620345
A Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Crinone 8% Intravaginal Progesterone Gel 90 mg Daily for Luteal Support in In-Vitro Fertilization (LOTUS II)
- Conditions
- Female Infertility
- Interventions
- Drug: intravaginal progesterone gel 90 mg
- First Posted Date
- 2015-07-08
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- Abbott
- Target Recruit Count
- 1034
- Registration Number
- NCT02491437
- Locations
- 🇨🇳
First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
🇹🇭Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand
🇷🇺Scientific Research Center of Obstetrics, Gynecology and Perinatology n. a. Ac. V. I. Kulakova, Moscow, Russian Federation
Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor
- First Posted Date
- 2014-10-13
- Last Posted Date
- 2016-01-28
- Lead Sponsor
- Chulalongkorn University
- Target Recruit Count
- 48
- Registration Number
- NCT02262481
- Locations
- 🇹🇭
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Randomized Double-blind Controlled Trial of Use of Dydrogesterone in Threatened Miscarriage
- First Posted Date
- 2014-05-01
- Last Posted Date
- 2018-10-16
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 406
- Registration Number
- NCT02128685
- Locations
- 🇭🇰
Department of Obstetrics and Gynaecology, PYNEH, Chai Wan, Hong Kong
🇭🇰Department of Obstetrics & Gynaecology, Queen Mary Hospital, Hong Kong, Hong Kong
🇭🇰Department of Obstetrics & Gynaecology, Kwong Wah Hospital, Mong Kok, Hong Kong
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.