Dydrogesterone
- Generic Name
- Dydrogesterone
- Drug Type
- Small Molecule
- Chemical Formula
- C21H28O2
- CAS Number
- 152-62-5
- Unique Ingredient Identifier
- 90I02KLE8K
- Background
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
- Indication
Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history of habitual abortions.
- Associated Conditions
- Infertility, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome (PMS), Recurrent Miscarriages, Spontaneous Abortions
- Associated Therapies
- Assisted Reproductive Technology therapy, Menstrual Regulation
An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients
- Conditions
- Luteal Phase SupportIdiopathic Hypogonadotropic HypogonadismLuteal Phase Deficiency
- Interventions
- First Posted Date
- 2022-10-06
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Fudan University
- Target Recruit Count
- 46
- Registration Number
- NCT05569577
- Locations
- 🇨🇳
OB & GYN Hospital of Fudan University, Shanghai, Shanghai, China
🇨🇳Obstetrics and Gynecology Hospital of Fudan University, Shanghai, Shanghai, China
Luteal Phase Ovarian Stimulation With Follitropin Delta and Dydrogesterone
- Conditions
- Oocyte DonationOocyte Donors
- Interventions
- First Posted Date
- 2022-08-30
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- CRG UZ Brussel
- Target Recruit Count
- 50
- Registration Number
- NCT05521828
- Locations
- 🇧🇪
Brussels Ivf, Brüssel, Belgium
The Effect of Pretreatment With Dydrogesterone Vs Combined Estradiol Valerate and Dydrogestrone on Clinical Pregnancy Outcome of ICSI in PCOS Patients"
- Conditions
- PCOSICSI
- Interventions
- First Posted Date
- 2022-03-29
- Last Posted Date
- 2022-04-14
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 500
- Registration Number
- NCT05300841
Comparative Study to Evaluate the Efficacy and Safety of the Fixed-dose Combination of Estradiol / Dydrogesterone in Perimenopausal Women
- Conditions
- Perimenopausal DisorderHot Flashes
- Interventions
- First Posted Date
- 2021-12-14
- Last Posted Date
- 2022-01-06
- Lead Sponsor
- Scientific Research Institute of Public Health, Russian Federation
- Target Recruit Count
- 150
- Registration Number
- NCT05156814
- Locations
- 🇷🇺
Federal State Budget Institution "National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov", Moscow, Russian Federation
The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study
- Conditions
- Observational Study
- Interventions
- First Posted Date
- 2021-11-26
- Last Posted Date
- 2021-11-26
- Lead Sponsor
- NewGiza University
- Target Recruit Count
- 200
- Registration Number
- NCT05135013
Progestin-primed Ovarian Stimulation Protocol Versus GnRH Antagonist Protocol in Polycystic Ovary Syndrome Patients Undergoing IVF/ICSI Cycles
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
- Interventions
- First Posted Date
- 2021-11-09
- Last Posted Date
- 2021-11-09
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 200
- Registration Number
- NCT05112692
Oral Progesterone for Prevention of Miscarriage in Threatened Abortion
- First Posted Date
- 2021-03-09
- Last Posted Date
- 2023-08-30
- Lead Sponsor
- Chulalongkorn University
- Target Recruit Count
- 100
- Registration Number
- NCT04788108
- Locations
- 🇹🇭
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Oral Versus Vaginal Progesterone for Luteal Phase Supplementation in Frozen Embryo Transfer Cycles
- Conditions
- Frozen Embryo TransferDydrogesteroneHormone Replacement TherapyInfertility, Female
- Interventions
- First Posted Date
- 2021-02-17
- Last Posted Date
- 2024-06-14
- Lead Sponsor
- CRG UZ Brussel
- Target Recruit Count
- 150
- Registration Number
- NCT04758871
- Locations
- 🇧🇪
Brussels IVF, Brussels, Belgium
Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders
- Conditions
- Infertility, Female
- Interventions
- Drug: Combined Oral ContraceptiveDrug: Cyclo-Progynova
- First Posted Date
- 2020-09-03
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
- Target Recruit Count
- 90
- Registration Number
- NCT04537078
- Locations
- 🇪🇬
Elshatby University Maternity Hospital, Alexandria, Egypt
Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Patients Undergoing PGT-A
- Conditions
- Progestin-primed Ovarian StimulationGnRH AntagonistPreimplantation Genetic TestingEuploid Rate
- Interventions
- First Posted Date
- 2020-06-04
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
- Target Recruit Count
- 400
- Registration Number
- NCT04414748
- Locations
- 🇨🇳
Shanghai JiAi Genetics & IVF Institute, Shanghai, Shanghai, China
Drug Development Updates
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