Mecamylamine
- Generic Name
- Mecamylamine
- Brand Names
- Inversine, Vecamyl
- Drug Type
- Small Molecule
- Chemical Formula
- C11H21N
- CAS Number
- 60-40-2
- Unique Ingredient Identifier
- -
- Background
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
- Indication
For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
- Associated Conditions
- Severe Hypertension, Moderate Hypertension, Uncomplicated Malignant hypertension
- Associated Therapies
- -
Treatment to Quit Smoking
Phase 2
Completed
- Conditions
- First Posted Date
- 2001-07-05
- Last Posted Date
- 2009-01-21
- Lead Sponsor
- US Department of Veterans Affairs
- Registration Number
- NCT00018161
- Locations
- 🇺🇸
Veterans Affairs Medical Center, Durham, North Carolina, United States
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