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Bacitracin

Generic Name
Bacitracin
Brand Names
Baciguent, Baciject, Cortisporin, Diosporin, Diphen, Neo-polycin, Neo-polycin HC, Neosporin Ointment, Neosporin Plus Maximum Strength, Neosporin Solution, Polycin-B, Polysporin, Procomycin, Rash Relief Antibacterial, Triple Antibiotic
Drug Type
Small Molecule
Chemical Formula
C66H103N17O16S
CAS Number
1405-87-4
Unique Ingredient Identifier
DDA3RRX0P7

Overview

Bacitracin is a combination of at least 9 bacitracins. 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.

Background

Bacitracin is a combination of at least 9 bacitracins. 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.

Indication

Bacitracin is indicated in topical formulations for acute and chronic localized skin infections. Occasionally, it is also used intramuscularly for infantile streptococcal pneumonia and empyema. Bacitracin is also formulated as an ointment with neomycin and polymyxin B for over the counter use. A bacitracin ointment formulated with neomycin and polymyxin B along with hydrocortisone is indicated for the treatment of corticosteroid responsive dermatoses with secondary infection.

Associated Conditions

  • Acne
  • Bacterial Infections of the Intestine
  • Empyema
  • Eye Infections
  • Infection
  • Inflammatory Reaction caused by Acne
  • Ocular Inflammatory Disease
  • Pneumonia
  • Skin Ulcer
  • Wound
  • Wound Infections
  • Corticosteroid-responsive dermatoses
  • Infection in minor cuts, scrapes, or burns

FDA Approved Products

POLYCIN
Manufacturer:DIRECT RX
Route:OPHTHALMIC
Strength:500 [USP'U] in 1 g
Approved: 2020/01/21
NDC:61919-111
Neomycin and Polymyxin B Sulfates and Bacitracin Zinc
Manufacturer:Bausch & Lomb Incorporated
Route:OPHTHALMIC
Strength:400 [USP'U] in 1 g
Approved: 2023/06/30
NDC:24208-780
Neomycin and Polymyxin B Sulfates and Bacitracin Zinc
Manufacturer:Rising Pharma Holdings, Inc.
Route:OPHTHALMIC
Strength:400 [USP'U] in 1 g
Approved: 2021/11/15
NDC:16571-754
BACIGUENT
Manufacturer:Woodward Pharma Services LLC
Route:OPHTHALMIC
Strength:500 [USP'U] in 1 g
Approved: 2018/11/12
NDC:69784-880
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone
Manufacturer:MWI/VetOne
Route:OPHTHALMIC
Strength:400 [USP'U] in 1 g
Approved: 2010/10/05
NDC:13985-016

Singapore Approved Products

BANEOCIN POWDER
Manufacturer:PHARMAZEUTISCHE FABRIK MONTAVIT GMBH
Form:POWDER
Strength:250 iu/g
Online:Yes
Approved: 1988/05/03
Approval:SIN00678P
POLYBAMYCIN OINT.
Manufacturer:SHIN POONG PHARMACEUTICAL CO LTD
Form:OINTMENT
Strength:400 u/g
Online:Yes
Approved: 1990/05/03
Approval:SIN04413P

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