Anlotinib

Generic Name
Anlotinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C23H22FN3O3
CAS Number
1058156-90-3
Unique Ingredient Identifier
GKF8S4C432
Background

Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.

Indication

用于治疗非小细胞肺癌、结直肠癌、肾癌、软组织肉瘤、甲状腺癌、胃癌等。

用于无法手术的局部晚期或转移性甲状腺髓样癌患者的治疗。

Associated Conditions
-
Associated Therapies
-

Phase II Study of Anlotinib in Patients With Advanced Renal Cell Carcinoma That Have Failed Or Are Intolerant To TKIs Therapy

Phase 2
Conditions
Interventions
First Posted Date
2014-02-26
Last Posted Date
2017-12-29
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
60
Registration Number
NCT02072044
Locations
🇨🇳

Cancer Hospital of Fudan University, Shanghai, Shanghai, China

🇨🇳

Chongqing Cancer Hospital, Chongqing, Chongqing, China

🇨🇳

Tianjin Medical University Cancer Hospital, Tianjin, Tianjin, China

and more 12 locations

To Predict Efficacy by Detecting Circulating Endothelial Cell Subsets and Blood Perfusion Parameters Changes in Vivo Tumor in the Phase II/III Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer

First Posted Date
2014-01-07
Last Posted Date
2016-12-16
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
110
Registration Number
NCT02029209
Locations
🇨🇳

20th Floor, Block C, Lake Road, Hexi District, Tianjin Medical University Cancer Institute and Hospital ., Tianjin, Tianjin, China

Phase II Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer(ALTER0302)

First Posted Date
2013-08-16
Last Posted Date
2015-10-28
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
117
Registration Number
NCT01924195
Locations
🇨🇳

Hunan Province Tumor Hospital, Changsha, Hunan, China

🇨🇳

Shanghai Changhai Hospital, Shanghai, Shanghai, China

🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

and more 10 locations

A Phase II Study of Anlotinib in STS Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-06-17
Last Posted Date
2019-05-22
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
166
Registration Number
NCT01878448
Locations
🇨🇳

Chinese PLA General Hospital, Beijing, Beijing, China

🇨🇳

Beijing Jishuitan Hospital, Beijing, Beijing, China

🇨🇳

Fujian Province Cancer Hospital, Fuzhou, Fujian, China

and more 13 locations

A Phase II Study of Anlotinib in MTC Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-06-11
Last Posted Date
2019-05-21
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
58
Registration Number
NCT01874873
Locations
🇨🇳

Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, Beijing, China

🇨🇳

The first hospital affiliated to fujian medical university, Fuzhou, Fujian, China

🇨🇳

Gansu Province Tumor Hospital, Lanzhou, Gansu, China

and more 7 locations

A Phase I Study of Anlotinib on Tolerance and Pharmacokinetics

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-04-17
Last Posted Date
2015-10-28
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
35
Registration Number
NCT01833923
Locations
🇨🇳

Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, Beijing, China

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