Ramelteon
- Generic Name
- Ramelteon
- Brand Names
- Rozerem
- Drug Type
- Small Molecule
- Chemical Formula
- C16H21NO2
- CAS Number
- 196597-26-9
- Unique Ingredient Identifier
- 901AS54I69
- Background
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
- Indication
用于失眠症，特别适用于治疗难以入睡型失眠症。
- Associated Conditions
- Insomnia
A Study of Ramelteon in Chinese Patients With Chronic Insomnia
- Conditions
- Chronic Insomnia
- Interventions
- First Posted Date
- 2024-07-22
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
- Target Recruit Count
- 280
- Registration Number
- NCT06512363
Insomnia Prevalence and Treatment Impact on Systemic Hypertension
- Conditions
- HypertensionInsomnia
- Interventions
- Behavioral: sleep hygiene
- First Posted Date
- 2022-06-10
- Last Posted Date
- 2022-12-29
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 5
- Registration Number
- NCT05414864
- Locations
- 🇧🇷
Heart Institute (InCor), São Paulo, Sao Paulo, Brazil
Delirium Reduction With Ramelteon
- First Posted Date
- 2021-10-06
- Last Posted Date
- 2024-08-22
- Lead Sponsor
- Centennial Medical Center
- Target Recruit Count
- 506
- Registration Number
- NCT05069428
- Locations
- 🇺🇸
Centennial Medical Center, Nashville, Tennessee, United States
Melatonin Agonist on Hospitalized Patients With Confirmed or Suspected COVID-19
- First Posted Date
- 2020-07-14
- Last Posted Date
- 2020-07-24
- Lead Sponsor
- Associação Fundo de Incentivo à Pesquisa
- Target Recruit Count
- 100
- Registration Number
- NCT04470297
The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU
- First Posted Date
- 2019-04-30
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Rhode Island Hospital
- Target Recruit Count
- 112
- Registration Number
- NCT03931070
- Locations
- 🇺🇸
Rhode Island Hospital, Providence, Rhode Island, United States
The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
- Target Recruit Count
- 17
- Registration Number
- NCT03461042
- Locations
- 🇯🇵
Yoyogi Sleep Disorder Clinic, Foundation of Sleep and Health Science, Shibuya-ku, Tokyo, Japan
Ramelteon for Complex Insomnia in Veterans With PTSD
- First Posted Date
- 2017-08-29
- Last Posted Date
- 2021-04-09
- Lead Sponsor
- State University of New York at Buffalo
- Registration Number
- NCT03265951
- Locations
- 🇺🇸
Veterans Affairs Medical Center in Buffalo, Buffalo, New York, United States
Ramelteon vs Placebo for Prevention of Delirium and Improvement of Sleep in Hospitalized Older Adults
- First Posted Date
- 2017-05-24
- Last Posted Date
- 2020-01-22
- Lead Sponsor
- Brigham and Women's Hospital
- Registration Number
- NCT03165695
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Ramelteon for Treatment of Insomnia in Cirrhosis
- First Posted Date
- 2017-03-27
- Last Posted Date
- 2021-03-29
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 10
- Registration Number
- NCT03091738
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
Ramelteon and Citicoline for Delirium
- First Posted Date
- 2016-07-21
- Last Posted Date
- 2017-11-09
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Registration Number
- NCT02840591
- Locations
- 🇺🇸
The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States
Drug Development Updates
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