Citicoline
- Generic Name
- Citicoline
- Drug Type
- Small Molecule
- Chemical Formula
- C14H26N4O11P2
- CAS Number
- 987-78-0
- Unique Ingredient Identifier
- 536BQ2JVC7
- Background
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
- Indication
主要用于急性颅脑外伤和脑手术后的意识障碍，以及脑卒中而致偏瘫的患者；也用于耳鸣及神经性耳聋、急性中毒、感染、大面积脑梗死所致的昏迷和意识障碍、帕金森病、急性胰腺炎；对缺血性脑血管病和血管性痴呆也有一定疗效,但对颅内出血引起的意识障碍效果较差。
- Associated Conditions
- Degenerative Brain Disorder, Parkinsonian Syndromes
Role of Citicoline in Treatment of Neonates With Hypoxic Ischemic Encephalopathy
- Conditions
- Hypoxic Ischemic Encephalopathy of Newborn
- Interventions
- First Posted Date
- 2024-07-26
- Last Posted Date
- 2024-08-14
- Lead Sponsor
- Armed Forces Hospital, Pakistan
- Target Recruit Count
- 200
- Registration Number
- NCT06522581
- Locations
- 🇵🇰
MH, Rawalpindi, Pakistan
Citicoline in Ischemic Stroke, a Randomized Trial
- First Posted Date
- 2024-01-18
- Last Posted Date
- 2024-01-18
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 800
- Registration Number
- NCT06210646
- Locations
- 🇪🇬
Kafr Elsheikh University Hospital, Kafr Ash Shaykh, Egypt
Supplemental Citicoline Administration to Reduce Lung Injury Efficacy Trial (SCARLET)
- First Posted Date
- 2023-05-31
- Last Posted Date
- 2025-04-02
- Lead Sponsor
- Ohio State University
- Target Recruit Count
- 80
- Registration Number
- NCT05881135
- Locations
- 🇺🇸
The Ohio State Wexner Medical Center, Columbus, Ohio, United States
Citicoline in Youth Alcohol Use Disorder
- Conditions
- Alcohol Use Disorder
- Interventions
- Drug: Placebo oral capsule
- First Posted Date
- 2023-05-23
- Last Posted Date
- 2024-10-14
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 48
- Registration Number
- NCT05870111
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma
- Conditions
- Glaucoma, Open-Angle
- Interventions
- Drug: Placebo
- First Posted Date
- 2023-02-02
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- Omikron Italia S.r.l.
- Target Recruit Count
- 1000
- Registration Number
- NCT05710198
- Locations
- 🇮🇹
Presidio Ospedale San Paolo, Milano, MI, Italy
Citicoline in Ischemic Stroke
- First Posted Date
- 2021-12-13
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 200
- Registration Number
- NCT05154903
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
The Impact of Air Travel on Passenger Cognitive Functions
- Conditions
- Air Travel
- Interventions
- Drug: Cytochrome C6Drug: Sodium Chloride Oral ProductDrug: Sodium Citrate Oral ProductDrug: Dextrose Oral Tablet, ChewableDrug: Probiotic Formula
- First Posted Date
- 2021-03-17
- Last Posted Date
- 2021-03-17
- Lead Sponsor
- Dinara Zhumanbayeva
- Target Recruit Count
- 50
- Registration Number
- NCT04802785
Citicoline Concentration in Human Vitreous
- First Posted Date
- 2019-07-01
- Last Posted Date
- 2019-07-01
- Lead Sponsor
- Istituto di Ricerca Neuroftalmologia S.r.l.
- Target Recruit Count
- 26
- Registration Number
- NCT04003090
- Locations
- 🇮🇹
Fondazione G.B. Bietti- IRCCS, Roma, Italy
Citicoline as Neuroprotector in Preterm
- First Posted Date
- 2019-05-29
- Last Posted Date
- 2019-05-29
- Lead Sponsor
- Sherief Abd-Elsalam
- Target Recruit Count
- 40
- Registration Number
- NCT03966170
- Locations
- 🇪🇬
Sherief Abd-Elsalam, Tanta, Egypt
Citicoline as Neuroprotector in Neonates Exposed to Hypoxia
- First Posted Date
- 2019-05-14
- Last Posted Date
- 2019-05-29
- Lead Sponsor
- Sherief Abd-Elsalam
- Target Recruit Count
- 40
- Registration Number
- NCT03949049
- Locations
- 🇪🇬
Sherief Abd-Elsalam, Cairo, Egypt
Drug Development Updates
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