Ramelteon
- Generic Name
- Ramelteon
- Brand Names
- Rozerem
- Drug Type
- Small Molecule
- Chemical Formula
- C16H21NO2
- CAS Number
- 196597-26-9
- Unique Ingredient Identifier
- 901AS54I69
- Background
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
- Indication
用于失眠症，特别适用于治疗难以入睡型失眠症。
- Associated Conditions
- Insomnia
- Associated Therapies
- -
A Study of Ramelteon in Chinese Patients With Chronic Insomnia
- Conditions
- Interventions
- First Posted Date
- 2024-07-22
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
- Target Recruit Count
- 280
- Registration Number
- NCT06512363
The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU
- First Posted Date
- 2019-04-30
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Rhode Island Hospital
- Target Recruit Count
- 112
- Registration Number
- NCT03931070
- Locations
- 🇺🇸
Rhode Island Hospital, Providence, Rhode Island, United States
Ramelteon for Complex Insomnia in Veterans With PTSD
- First Posted Date
- 2017-08-29
- Last Posted Date
- 2021-04-09
- Lead Sponsor
- State University of New York at Buffalo
- Registration Number
- NCT03265951
- Locations
- 🇺🇸
Veterans Affairs Medical Center in Buffalo, Buffalo, New York, United States
Ramelteon vs Placebo for Prevention of Delirium and Improvement of Sleep in Hospitalized Older Adults
- First Posted Date
- 2017-05-24
- Last Posted Date
- 2020-01-22
- Lead Sponsor
- Brigham and Women's Hospital
- Registration Number
- NCT03165695
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Ramelteon and Citicoline for Delirium
- First Posted Date
- 2016-07-21
- Last Posted Date
- 2017-11-09
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Registration Number
- NCT02840591
- Locations
- 🇺🇸
The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States
The Impact of Ramelteon on Sleep and Delirium in Patients Who Undergo Pulmonary Thromboendarterectomy (PTE) Surgery
- First Posted Date
- 2016-02-24
- Last Posted Date
- 2022-02-08
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 120
- Registration Number
- NCT02691013
The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy
- First Posted Date
- 2016-01-29
- Last Posted Date
- 2019-07-22
- Lead Sponsor
- Takeda
- Target Recruit Count
- 26
- Registration Number
- NCT02669082
- Locations
- 🇯🇵
Sangenjaya Neurology and Psychosomatic Clinic, Setagaya, Tokyo, Japan
🇯🇵Himorogi Kokorono Clinic, Shinjuku, Tokyo, Japan
🇯🇵Ishikawa Mental Clinic, Sapporo, Hokkaido, Japan
Ramelteon Prevention of Delirium - RCT
- First Posted Date
- 2015-10-01
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- Hartford Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT02564939
- Locations
- 🇺🇸
Hartford Hospital, Hartford, Connecticut, United States
Effect of Ramelteon on Smoking Abstinence
- First Posted Date
- 2015-09-25
- Last Posted Date
- 2019-11-04
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 140
- Registration Number
- NCT02560324
- Locations
- 🇺🇸
Center for Interdisciplinary Research on Nicotine Addiction, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
Ramelteon in the Prevention of Post-operative Delirium
- First Posted Date
- 2014-12-24
- Last Posted Date
- 2020-06-30
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 80
- Registration Number
- NCT02324153
- Locations
- 🇺🇸
Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.