Sodium nitroprusside
- Generic Name
- Sodium nitroprusside
- Brand Names
- Nipride, Nipride RTU, Nitropress
- Drug Type
- Small Molecule
- Chemical Formula
- C5FeN6O
- CAS Number
- 15078-28-1
- Unique Ingredient Identifier
- 169D1260KM
Overview
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Background
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Indication
For immediate reduction of blood pressure of patients in hypertensive crises, reduce bleeding during surgery, and for the treatment of acute congestive heart failure
Associated Conditions
- Acute Heart Failure (AHF)
- Hypertensive crisis
- Intraoperative Blood Loss
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2019/06/28 | Early Phase 1 | Terminated | |||
2019/06/04 | Early Phase 1 | Withdrawn | |||
2019/05/16 | Phase 1 | Terminated | |||
2018/11/13 | Early Phase 1 | Completed | |||
2018/09/21 | Phase 1 | Completed | |||
2018/09/20 | Phase 1 | Completed | |||
2018/02/27 | Phase 2 | Terminated | |||
2018/01/23 | Not Applicable | UNKNOWN | The First Affiliated Hospital of Zhengzhou University | ||
2018/01/23 | Not Applicable | UNKNOWN | The First Affiliated Hospital of Zhengzhou University | ||
2017/10/23 | Not Applicable | Completed |
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
Sodium Nitroprusside | Caplin Steriles Limited | INTRAVENOUS | 50 mg in 2 mL | 2017/11/29 | 65145-101 |
NIPRIDE RTU | EXELA PHARMA SCIENCES, LLC | INTRAVENOUS | 0.2 mg in 1 mL | 2018/07/20 | 51754-1018 |
NIPRIDE RTU | EXELA PHARMA SCIENCES, LLC | INTRAVENOUS | 0.2 mg in 1 mL | 2018/07/20 | 51754-1029 |
sodium nitroprusside | Nexus Pharmaceuticals Inc | INTRAVENOUS | 25 mg in 1 mL | 2022/05/09 | 14789-012 |
SODIUM NITROPRUSSIDE | Armas Pharmaceuticals Inc. | INTRAVENOUS | 50 mg in 2 mL | 2021/09/17 | 72485-305 |
sodium nitroprusside in 0.9% sodium chloride | Slate Run Pharmaceuticals, LLC | INTRAVENOUS | 0.2 mg in 1 mL | 2023/11/15 | 70436-206 |
Sodium Nitroprusside | BE Pharmaceuticals Inc. | INTRAVENOUS | 50 mg in 2 mL | 2021/07/22 | 71839-120 |
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
|---|
No EMA products found
No EMA products found for this drug
Singapore Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. | Online |
|---|
No Singapore products found
No Singapore products found for this drug
China Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|---|---|---|---|---|---|---|---|---|
Sodium Nitroprusside for Injection | 国药准字H20143166 | 仲景宛西制药股份有限公司 | 注射剂 | N/A | 50mg(相当于无水物43.96mg) | Chemical Drug | Approved | 2014/06/06 | Domestic |
Sodium Nitroprusside for Injection | 国药准字H20093909 | 广东众生药业股份有限公司 | 注射剂 | N/A | 50mg | Chemical Drug | Approved | 2024/04/09 | Domestic |
Sodium Nitroprusside for Injection | 国药准字H20054536 | 开封康诺药业有限公司 | 注射剂 | N/A | 50mg(相当于无水物43.96mg) | Chemical Drug | Approved | 2020/05/25 | Domestic |
Sodium Nitroprusside for Injection | 国药准字H20083888 | 浙江佐力药业股份有限公司 | 注射剂 | N/A | 50mg | Chemical Drug | Approved | 2022/12/20 | Domestic |
Sodium Nitroprusside for Injection | 国药准字H20064559 | 广东宏远集团药业有限公司 | 注射剂 | N/A | 50mg [按Na2Fe(CN)5NO.2H2O计] | Chemical Drug | Approved | 2020/12/15 | Domestic |
Sodium Nitroprusside for Injection | 国药准字H11021635 | 华润双鹤药业股份有限公司 | 注射剂(冻干粉针剂) | N/A | 50mg[按Na2Fe(CN)5NO•2H2O计] | Chemical Drug | Approved | 2020/10/12 | Domestic |
Australia Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|
No Australia products found
No Australia products found for this drug