Choriogonadotropin alfa
- Generic Name
- Choriogonadotropin alfa
- Brand Names
- Ovidrel, Ovitrelle, Pregnyl
- Drug Type
- Biotech
- CAS Number
- 177073-44-8
- Unique Ingredient Identifier
- 6413W06WR3
- Background
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH and LH.
- Indication
For the treatment of female infertility
- Associated Conditions
- Secondary Hypogonadotrophic hypogonadism
- Associated Therapies
- Assisted Reproductive Technology therapy, Ovulation induction therapy
Clinical Study of Recombinant Human Follitropin for Injection Assisted in COH Assisted IVF-ET
- Conditions
- Ovarian Hyperstimulation Syndrome
- Interventions
- First Posted Date
- 2017-03-06
- Last Posted Date
- 2017-03-06
- Lead Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
- Target Recruit Count
- 252
- Registration Number
- NCT03071172
- Locations
- 🇨🇳
Sun Yat-sen Memorial Hospital, Guangzhou, Guangdong, China
🇨🇳Peking University Third Hospital, Beijing, China
🇨🇳The first Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study
- Conditions
- Luteal SupportEmbryo Transfer
- Interventions
- First Posted Date
- 2016-07-07
- Last Posted Date
- 2016-12-13
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 62
- Registration Number
- NCT02825290
- Locations
- 🇮🇱
Sheba medical center, Ramat Gan, Israel
Effect of Treatment With Corifollitropin Alpha in Vitro Fertilization in Patients With Poor Ovarian Response.
- Conditions
- Infertility
- Interventions
- Drug: Micronized natural progesterone.
- First Posted Date
- 2014-04-21
- Last Posted Date
- 2017-06-12
- Lead Sponsor
- Instituto de Investigacion Sanitaria La Fe
- Target Recruit Count
- 234
- Registration Number
- NCT02118051
- Locations
- 🇪🇸
Human Reproduction Unit of the La Fe University and Politechnic Hospital, Valencia, Spain
Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women
- Conditions
- Oligo-ovulationAnovulationPolycystic Ovarian SyndromeHypothalamic-pituitary Dysfunction
- Interventions
- First Posted Date
- 2012-07-31
- Last Posted Date
- 2016-01-07
- Lead Sponsor
- Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 81
- Registration Number
- NCT01653743
- Locations
- 🇯🇵
Bashamichi Ladies Clinic, Kanagawa, Japan
🇯🇵Hanabusa Women's Central Fertility Clinic, Hyogo, Japan
🇯🇵Sophia Ladies Clinic, Kanagawa, Japan
EXpression PRofile Endometrium Samples Study
- Conditions
- In Vitro Fertilization
- Interventions
- Drug: Gonal -f® [r-hFSH]Drug: Gonadotropin-releasing hormone (GnRH) AgonistDrug: Gonadotropin-releasing hormone (GnRH) Antagonist
- First Posted Date
- 2010-09-28
- Last Posted Date
- 2013-12-27
- Lead Sponsor
- Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 27
- Registration Number
- NCT01210144
- Locations
- 🇫🇷
Research Site, Paris, France
Human Chorionic Gonadotropin Supplementation Prior to In-vitro Fertilization Treatment in Poor Responders
- First Posted Date
- 2010-09-20
- Last Posted Date
- 2011-03-02
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 100
- Registration Number
- NCT01205009
- Locations
- 🇮🇱
Hadassah Medical Center, Jerusalem, Israel
Drug Development Updates
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