MedPath

Enoxaparin sodium

Generic Name
Enoxaparin sodium
Brand Names
Lovenox, Inhixa
Drug Type
Small Molecule
CAS Number
9005-49-6
Unique Ingredient Identifier
E47C0NF7LV

Overview

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated heparin, without increasing the risk of serious bleeding.

Background

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated heparin, without increasing the risk of serious bleeding.

Indication

Enoxaparin is indicated for the prevention of ischemic complications in unstable angina and in non Q-wave myocardial infarction; it is indicated in conjunction with percutaneous intervention and/or other treatment for the management of acute ST elevation myocardial infarction. Enoxaparin is also indicated in the prophylaxis of DVT in abdominal surgery, hip replacement, knee replacement, or medical patients with severely restricted mobility during acute illness. Additionally, enoxaparin is indicated for the inpatient treatment of DVT with or without pulmonary embolism and the treatment of outpatient DVT without pulmonary embolism.

Associated Conditions

  • Acute Coronary Syndrome (ACS)
  • Acute Myocardial Infarction With ST Segment Elevation
  • Deep Vein Thrombosis
  • Ischemic complications caused by non-q wave myocardial infarction
  • Ischemic complications caused by unstable angina

FDA Approved Products

Enoxaparin Sodium
Manufacturer:Zydus Pharmaceuticals USA Inc.
Route:INTRAVENOUS, SUBCUTANEOUS
Strength:80 mg in 0.8 mL
Approved: 2023/10/05
NDC:70710-1760
Enoxaparin Sodium
Manufacturer:NorthStar RxLLC
Route:SUBCUTANEOUS
Strength:40 mg in 0.4 mL
Approved: 2023/08/30
NDC:72603-175
Enoxaparin Sodium
Manufacturer:Apotex Corp.
Route:SUBCUTANEOUS
Strength:40 mg in 0.4 mL
Approved: 2023/07/21
NDC:60505-0792
Enoxaparin Sodium
Manufacturer:NorthStar RxLLC
Route:SUBCUTANEOUS
Strength:80 mg in 0.8 mL
Approved: 2023/08/30
NDC:72603-195
Enoxaparin Sodium
Manufacturer:NorthStar RxLLC
Route:SUBCUTANEOUS
Strength:60 mg in 0.6 mL
Approved: 2023/08/30
NDC:72603-185

Singapore Approved Products

INHIXA Solution for Injection 6000 Anti-Xa IU (60MG)/0.6ML
Manufacturer:Shenzhen Techdow Pharmaceutical Co., Ltd.
Form:INJECTION, SOLUTION
Strength:6000 IU (60 MG)/0.6 ML
Online:Yes
Approved: 2024/05/07
Approval:SIN16997P
INHIXA Solution for Injection 2000 Anti-Xa IU (20MG)/0.2ML
Manufacturer:Shenzhen Techdow Pharmaceutical Co., Ltd.
Form:INJECTION, SOLUTION
Strength:2000 IU (20 MG)/0.2 ML
Online:Yes
Approved: 2024/05/07
Approval:SIN16999P
CLEXANE INJECTION 8000 IU (80mg)/0.8 ml
Manufacturer:Sanofi Winthrop Industrie
Form:INJECTION
Strength:8000 IU (80mg)/0.8ml
Online:Yes
Approved: 2012/02/06
Approval:SIN14094P
INHIXA Solution for Injection 4000 Anti-Xa IU (40MG)/0.4ML
Manufacturer:Shenzhen Techdow Pharmaceutical Co., Ltd.
Form:INJECTION, SOLUTION
Strength:4000 IU (40 MG)/0.4 ML
Online:Yes
Approved: 2024/05/07
Approval:SIN16998P
CLEXANE INJECTION 4000 IU (40mg)/0.4 ml
Manufacturer:Sanofi Winthrop Industrie
Form:INJECTION
Strength:4000 IU (40mg)/0.4 ml
Online:Yes
Approved: 2012/02/06
Approval:SIN14095P

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath