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Retagliptin

Generic Name
Retagliptin
Drug Type
Small Molecule
Chemical Formula
C19H18F6N4O3
CAS Number
1174122-54-3
Unique Ingredient Identifier
328C4R3P9L
Background

Retagliptin is under investigation in clinical trial NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients).

Indication

用于改善成人2型糖尿病患者的血糖控制。

①单药:本品单药可配合饮食控制和运动,改善成人2型糖尿病患者的血糖控制。

②与盐酸二甲双胍联合使用:在单独使用盐酸二甲双胍血糖控制不佳时,本品可与盐酸二甲双胍联合使用,配合饮食和运动改善成人2型糖尿病患者的血糖控制。

SP2086 Pharmacokinetic Study in Renal Insufficiency Patients

Phase 1
Completed
Conditions
Renal Insufficiency
Interventions
First Posted Date
2016-06-28
Last Posted Date
2016-06-28
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
30
Registration Number
NCT02815774

The Drug-drug Interaction of SP2086 and Simvastatin

Phase 1
Completed
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2016-06-28
Last Posted Date
2016-06-28
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
16
Registration Number
NCT02815722
Locations
🇨🇳

People's Liberation Army General Hospital of Chengdu Military Region, Chengdu, China

The Drug-drug Interaction of SP2086 and Metformin

Phase 1
Completed
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2016-06-27
Last Posted Date
2016-06-27
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
24
Registration Number
NCT02813863

Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes

Phase 2
Completed
Conditions
Type 2 Diabetes
Interventions
Drug: Placebo
First Posted Date
2013-11-14
Last Posted Date
2013-11-19
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
120
Registration Number
NCT01984489
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