Citalopram

Generic Name
Citalopram
Brand Names
Celexa, Ctp
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
59729-33-8
Unique Ingredient Identifier
0DHU5B8D6V
Background

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...

Indication

Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.

Associated Conditions
Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
Associated Therapies
-
Clinical Trials
Related News

Trial of Citalopram for the Prevention of Depression

First Posted Date
2006-04-25
Last Posted Date
2017-05-22
Lead Sponsor
Marina Klein
Target Recruit Count
76
Registration Number
NCT00317746
Locations
🇨🇦

Immunodeficiency Service Montreal Chest Institute McGill University Health Centre, Montreal, Quebec, Canada

Serotonin, Impulsivity, and Cocaine Dependence Treatment

Phase 2
Completed
Conditions
Cocaine Dependence
First Posted Date
2006-02-28
Last Posted Date
2017-01-12
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
120
Registration Number
NCT00297505
Locations
🇺🇸

University of Texas - Houston Health Science Center, Houston, Texas, United States

The Role of Cytokine-Serotonin Interactions in Post-Stroke Depression

Phase 4
Completed
Conditions
Depression
First Posted Date
2005-11-15
Last Posted Date
2017-04-28
Lead Sponsor
Sunnybrook Health Sciences Centre
Target Recruit Count
138
Registration Number
NCT00254020
Locations
🇨🇦

York Central Hospital, Richmond Hill, Ontario, Canada

🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

🇨🇦

Baycrest, Toronto, Ontario, Canada

and more 2 locations

Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents

Phase 3
Withdrawn
Conditions
Major Depression
First Posted Date
2005-11-07
Last Posted Date
2006-09-19
Lead Sponsor
Sunnybrook Health Sciences Centre
Target Recruit Count
60
Registration Number
NCT00249886
Locations
🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

Alcohol and Gender Effects on Stress Circuit Function

Not Applicable
Completed
Conditions
Stress
Alcohol Dependence
Alcoholism
Interventions
Other: Placebo
Drug: Citalopram
First Posted Date
2005-09-27
Last Posted Date
2014-01-07
Lead Sponsor
University of Cincinnati
Target Recruit Count
96
Registration Number
NCT00226694
Locations
🇺🇸

The Department of Veterans Affairs / Veterans Healthcare System of Ohio, Cincinnati, Ohio, United States

Effects of Citalopram on Hostility and CHD Risk

Not Applicable
Completed
Conditions
Heart Diseases
Cardiovascular Diseases
First Posted Date
2005-09-22
Last Posted Date
2014-06-11
Lead Sponsor
University of Pittsburgh
Registration Number
NCT00217828

Treatment of Citalopram for Anxiety Disorders Following a Traumatic Brain Injury

Not Applicable
Conditions
Traumatic Brain Injury
First Posted Date
2005-09-21
Last Posted Date
2007-10-05
Lead Sponsor
Walter Reed Army Medical Center
Target Recruit Count
104
Registration Number
NCT00208572
Locations
🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Effect of the Menstrual Cycle on the Symptoms of Depression and Treatment Response

Not Applicable
Completed
Conditions
Major Depressive Disorder
Depression
First Posted Date
2005-09-16
Last Posted Date
2009-03-13
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
44
Registration Number
NCT00188396
Locations
🇨🇦

University Health Network, Toronto, Ontario, Canada

Antidepressant Maintenance in Traumatic Brain Injury

Phase 4
Conditions
Depression
Interventions
Drug: Placebo
Drug: citalopram
First Posted Date
2005-09-13
Last Posted Date
2008-06-04
Lead Sponsor
Ontario Neurotrauma Foundation
Target Recruit Count
21
Registration Number
NCT00162916
Locations
🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

Specific Effects of Escitalopram on Neuroendocrine Response

Completed
Conditions
Healthy
First Posted Date
2005-09-08
Last Posted Date
2009-02-05
Lead Sponsor
Queen's University
Target Recruit Count
8
Registration Number
NCT00150527
Locations
🇨🇦

Providence Centre, Mental Health Services, Kingston, Ontario, Canada

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