Acetazolamide
- Generic Name
- Acetazolamide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C4H6N4O3S2
- CAS Number
- 59-66-5
- Unique Ingredient Identifier
- O3FX965V0I
- Background
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of...
- Indication
For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma
- Associated Conditions
- Acute angle-closure glaucoma, Edema, Familial periodic paralysis, Generalized Tonic-Clonic Seizures, Metabolic Alkalosis, Open Angle Glaucoma (OAG), Other and unspecified effects of high altitude, Cystine renal calculi, Drug-induced edema, Nonuveitic secondary glaucoma, Salicylate intoxication
- Associated Therapies
- Urine alkalinization therapy
Pharmacological Countermeasures for High Altitude
- Conditions
- Interventions
- First Posted Date
- 2022-03-29
- Last Posted Date
- 2024-12-04
- Target Recruit Count
- 18
- Registration Number
- NCT05300477
- Locations
- 🇺🇸
USARIEM, Natick, Massachusetts, United States
Rescue Pharmacotherapy for OSA
- Conditions
- Interventions
- First Posted Date
- 2022-03-24
- Last Posted Date
- 2024-06-04
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 70
- Registration Number
- NCT05293600
- Locations
- 🇺🇸
Sleep Disorders Research Program Brigham and Women's Hospital, Boston, Massachusetts, United States
Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide
- Conditions
- Interventions
- First Posted Date
- 2021-08-27
- Last Posted Date
- 2022-10-03
- Lead Sponsor
- Ji Xunming,MD,PhD
- Target Recruit Count
- 252
- Registration Number
- NCT05023941
- Locations
- 🇨🇳
Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China
Acetazolamide Trial in Normal Pressure Hydrocephalus
- Conditions
- Interventions
- First Posted Date
- 2021-07-23
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Uppsala University Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT04975269
- Locations
- 🇸🇪
Department of Clinical Neurophysiology, Neurosurgery and Neurology, Uppsala University Hospital, Uppsala, Sweden
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
- Conditions
- Interventions
- First Posted Date
- 2021-06-07
- Last Posted Date
- 2022-11-02
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 100
- Registration Number
- NCT04915365
- Locations
- 🇰🇬
National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
Acetazolamide to Prevent Impending Altitude-illness in Patients With COPD
- Conditions
- Interventions
- First Posted Date
- 2021-06-04
- Last Posted Date
- 2023-03-03
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 100
- Registration Number
- NCT04913389
- Locations
- 🇰🇬
National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
Acetazolamide for Treatment Resistant Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2021-05-14
- Last Posted Date
- 2024-01-05
- Lead Sponsor
- Vishwajit Nimgaonkar, MD PhD
- Target Recruit Count
- 60
- Registration Number
- NCT04887792
- Locations
- 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇮🇳St John's Medical College Hospital, Bangalore, India
Optimal Dosage of Acetazolamide for OSA Treatment
- First Posted Date
- 2021-01-27
- Last Posted Date
- 2021-05-19
- Lead Sponsor
- University Hospital, Antwerp
- Target Recruit Count
- 100
- Registration Number
- NCT04726982
- Locations
- 🇧🇪
Antwerp University Hospital, Edegem, Antwerp, Belgium
Acetazolamide Efficacy in Ataxia in PMM2-CDG
- First Posted Date
- 2020-12-22
- Last Posted Date
- 2024-01-29
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 25
- Registration Number
- NCT04679389
- Locations
- 🇺🇸
Seattle Children's Hospital, Seattle, Washington, United States
🇺🇸Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸Mayo Clinic, Rochester, Minnesota, United States
Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea
- Conditions
- Interventions
- First Posted Date
- 2020-11-20
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 20
- Registration Number
- NCT04639193
- Locations
- 🇺🇸
Altman Clinical and Translational Research Institute Building, La Jolla, California, United States
🇺🇸UCSD Health - Pulmonary and Sleep Clinic, La Jolla, California, United States
Drug Development Updates
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