Acetazolamide
- Generic Name
- Acetazolamide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C4H6N4O3S2
- CAS Number
- 59-66-5
- Unique Ingredient Identifier
- O3FX965V0I
- Background
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of...
- Indication
For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma
- Associated Conditions
- Acute angle-closure glaucoma, Edema, Familial periodic paralysis, Generalized Tonic-Clonic Seizures, Metabolic Alkalosis, Open Angle Glaucoma (OAG), Other and unspecified effects of high altitude, Cystine renal calculi, Drug-induced edema, Nonuveitic secondary glaucoma, Salicylate intoxication
- Associated Therapies
- Urine alkalinization therapy
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
- Conditions
- Interventions
- First Posted Date
- 2024-08-02
- Last Posted Date
- 2024-08-05
- Lead Sponsor
- Helwan University
- Target Recruit Count
- 60
- Registration Number
- NCT06535529
- Locations
- 🇪🇬
Critical Care Medicine Department - Cairo University Hospitals., Cairo, Egypt
Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder
- Conditions
- Interventions
- First Posted Date
- 2024-07-26
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Sanjay R Patel
- Target Recruit Count
- 40
- Registration Number
- NCT06521476
- Locations
- 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men
- First Posted Date
- 2024-07-12
- Last Posted Date
- 2024-07-12
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 270
- Registration Number
- NCT06498505
- Locations
- 🇰🇬
National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to Men
- First Posted Date
- 2024-07-12
- Last Posted Date
- 2024-07-12
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 270
- Registration Number
- NCT06499727
- Locations
- 🇰🇬
National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men
- First Posted Date
- 2024-07-12
- Last Posted Date
- 2024-07-12
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 270
- Registration Number
- NCT06498531
- Locations
- 🇰🇬
National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload
- Conditions
- Interventions
- First Posted Date
- 2024-05-16
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 110
- Registration Number
- NCT06414759
- Locations
- 🇪🇬
National Heart Institute, Giza, GZ, Egypt
Optimal Diuretic Therapies for Acute Heart Failure with Volume Overload
- Conditions
- Interventions
- First Posted Date
- 2023-12-12
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Johannes Grand
- Target Recruit Count
- 939
- Registration Number
- NCT06166654
- Locations
- 🇩🇰
Bispebjerg Hospital, Copenhagen, Denmark
🇩🇰Herlev-Gentofte hospital, Copenhagen, Denmark
🇩🇰Amager-Hvidovre Hospital, Hvidovre, Capital Region of Denmark, Denmark
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients with OSA
- Conditions
- Interventions
- First Posted Date
- 2023-11-24
- Last Posted Date
- 2024-12-02
- Lead Sponsor
- Incannex Healthcare Ltd
- Target Recruit Count
- 560
- Registration Number
- NCT06146101
- Locations
- 🇺🇸
Desert Center for Allergy and Chest Diseases, Pheonix, Arizona, United States
🇺🇸Exalt Clinical Research, Chula Vista, California, United States
🇺🇸CenExel CNS- Los Alamitos, Long Beach, California, United States
The AXIS Study: the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in Retinoschisis
- First Posted Date
- 2023-11-02
- Last Posted Date
- 2024-12-06
- Target Recruit Count
- 19
- Registration Number
- NCT06114537
- Locations
- 🇳🇱
Amsterdam University Medical Centers, Amsterdam, Noord-Holland, Netherlands
Carbonic Anhydrase Inhibitors and Carbonation: A Novel Approach to Reduce Soda Consumption
- First Posted Date
- 2023-10-31
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- University of Arizona
- Target Recruit Count
- 44
- Registration Number
- NCT06110078
- Locations
- 🇺🇸
College of Medicine Phoenix U of Arizona, Phoenix, Arizona, United States
Drug Development Updates
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