Acetazolamide

Generic Name
Acetazolamide
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C4H6N4O3S2
CAS Number
59-66-5
Unique Ingredient Identifier
O3FX965V0I
Background

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of...

Indication

For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma

Associated Conditions
Acute angle-closure glaucoma, Edema, Familial periodic paralysis, Generalized Tonic-Clonic Seizures, Metabolic Alkalosis, Open Angle Glaucoma (OAG), Other and unspecified effects of high altitude, Cystine renal calculi, Drug-induced edema, Nonuveitic secondary glaucoma, Salicylate intoxication
Associated Therapies
Urine alkalinization therapy

Impact of Acetazolamide in Reducing Referred Postoperative Pain

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-07-14
Last Posted Date
2022-09-23
Lead Sponsor
Medical College of Wisconsin
Target Recruit Count
33
Registration Number
NCT04470843
Locations
🇺🇸

Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin, United States

Acetazolamide for the Prevention of Post Operative CSF Leak

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2020-04-17
Last Posted Date
2021-12-14
Lead Sponsor
University of Miami
Registration Number
NCT04351061
Locations
🇺🇸

University of Miami, Miami, Florida, United States

Treatment of Chronic Mountain Sickness

First Posted Date
2020-01-31
Last Posted Date
2021-08-20
Lead Sponsor
Centre d'Expertise sur l'Altitude EXALT
Target Recruit Count
60
Registration Number
NCT04251364
Locations
🇫🇷

Association EXALT, UM Sport Pathologies, Hôpital Sud, Avenue Kimberley, Échirolles, France

Acetazolamide Add-On Therapy to OSA Surgery

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-01-13
Last Posted Date
2024-06-18
Lead Sponsor
University Hospital, Antwerp
Target Recruit Count
26
Registration Number
NCT04227093
Locations
🇧🇪

Antwerp University Hospital, Edegem, Antwerp, Belgium

Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2019-05-24
Last Posted Date
2019-05-24
Lead Sponsor
Fayoum University
Target Recruit Count
48
Registration Number
NCT03963336
Locations
🇪🇬

Fayoum University Hospital, Fayoum, Egypt

Acetazolamide (AZ) for Management of Alkalosis in Bartter Syndrome

First Posted Date
2019-02-20
Last Posted Date
2019-02-20
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
20
Registration Number
NCT03847571
Locations
🇮🇷

Fateme Ghane Sharbaf, Mashhad, Iran, Islamic Republic of

🇮🇷

Semnan University of Medical Sciences, Semnan, Iran, Islamic Republic of

🇮🇷

Banafshe Dormansh, Tehran, Iran, Islamic Republic of

and more 1 locations

A Noninvasive Arterial Input Estimation Method for O-15 PET and Integrated PET/MR Scanning

First Posted Date
2019-01-16
Last Posted Date
2024-03-01
Lead Sponsor
University of Alabama at Birmingham
Registration Number
NCT03806751
Locations
🇺🇸

UAB Advanced Imaging Facility, Birmingham, Alabama, United States

Acetazolamide for Treating NPH in Shunt-candidates Patients

First Posted Date
2018-12-19
Last Posted Date
2018-12-19
Lead Sponsor
Rabin Medical Center
Target Recruit Count
15
Registration Number
NCT03779594
Locations
🇮🇱

Rabin Medical Center, Petah Tikva, Israel

Acetazolamide in Patients With Acute Heart Failure

First Posted Date
2018-10-25
Last Posted Date
2018-10-30
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
90
Registration Number
NCT03720288
Locations
🇧🇷

Instituto do Coração - HMFMUSP, São Paulo, Brazil

Cerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia

First Posted Date
2018-10-23
Last Posted Date
2024-10-30
Lead Sponsor
Children's Hospital Los Angeles
Target Recruit Count
165
Registration Number
NCT03715972
Locations
🇺🇸

CHLA, Los Angeles, California, United States

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