Bumetanide

Generic Name
Bumetanide
Brand Names
Bumex, Burinex
Drug Type
Small Molecule
Chemical Formula
C17H20N2O5S
CAS Number
28395-03-1
Unique Ingredient Identifier
0Y2S3XUQ5H
Background

Bumetanide is a sulfamyl diuretic.

Indication

For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.

Associated Conditions
Edema
Associated Therapies
-

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2024-06-20
Last Posted Date
2024-06-20
Lead Sponsor
Stefano Vicari
Target Recruit Count
64
Registration Number
NCT06465823
Locations
🇮🇹

Bambino Gesù Children's Hospital, Rome, Italy

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

First Posted Date
2024-01-23
Last Posted Date
2024-01-29
Lead Sponsor
Heart Center Research, LLC
Target Recruit Count
80
Registration Number
NCT06218199
Locations
🇺🇸

Heart Center Research, LLC, Huntsville, Alabama, United States

Bumetanide in Patients With Alzheimer's Disease

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-09-25
Last Posted Date
2024-04-12
Lead Sponsor
Stanford University
Target Recruit Count
40
Registration Number
NCT06052163
Locations
🇺🇸

Stanford University, Stanford, California, United States

A Study of Ultra High Dose Diuretics to Treat Heart Failure

First Posted Date
2023-09-14
Last Posted Date
2024-12-19
Lead Sponsor
Mayo Clinic
Target Recruit Count
20
Registration Number
NCT06036914
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Role of Bumetanide in Treatment of Autism

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2021-02-23
Last Posted Date
2021-02-23
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
80
Registration Number
NCT04766177
Locations
🇪🇬

Sherief Abd-Elsalam, Tanta, Egypt

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

First Posted Date
2019-04-23
Last Posted Date
2020-11-23
Lead Sponsor
Hospital General de México Dr. Eduardo Liceaga
Target Recruit Count
34
Registration Number
NCT03923933
Locations
🇲🇽

Hospital General de Mexico, Mexico City, Mexico

A Study of Bumetanide for the Treatment of Autism Spectrum Disorders

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-05-17
Last Posted Date
2021-03-01
Lead Sponsor
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Target Recruit Count
120
Registration Number
NCT03156153
Locations
🇨🇳

Xinhua Hospital, Shanghai, Shanghai, China

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

First Posted Date
2017-04-11
Last Posted Date
2024-04-30
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
30
Registration Number
NCT03107416
Locations
🇺🇸

Memorial Sloan Kettering Westchester (Consent and follow-up only), Harrison, New York, United States

🇺🇸

Memorial Sloan Kettering Basking Ridge (Consent and follow-up only), Basking Ridge, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Monmouth (Consent and follow-up only), Middletown, New Jersey, United States

and more 2 locations

Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2016-10-28
Last Posted Date
2021-06-02
Lead Sponsor
University Hospital, Limoges
Registration Number
NCT02947880

Diuretic/Cool Dialysate Trial

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2015-11-01
Last Posted Date
2024-01-11
Lead Sponsor
University of New Mexico
Target Recruit Count
11
Registration Number
NCT02593526
Locations
🇺🇸

Dialysis Clinic Inc. - Indian School, Albuquerque, New Mexico, United States

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