Isosorbide dinitrate

Generic Name
Isosorbide dinitrate
Brand Names
Bidil, Dilatrate, Isordil
Drug Type
Small Molecule
Chemical Formula
C6H8N2O8
CAS Number
87-33-2
Unique Ingredient Identifier
IA7306519N
Background

A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.

Indication

For the prevention of angina pectoris due to coronary artery disease.

Associated Conditions
Angina Pectoris, Heart Failure
Associated Therapies
-

Hypertensive Heart Failure Treatment in SSA

First Posted Date
2024-05-06
Last Posted Date
2024-05-06
Lead Sponsor
University of Abuja
Target Recruit Count
50
Registration Number
NCT06400784
Locations
🇳🇬

University of Abuja Teaching Hospital, Abuja, Federal Capital Territory, Nigeria

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

First Posted Date
2024-01-23
Last Posted Date
2024-01-29
Lead Sponsor
Heart Center Research, LLC
Target Recruit Count
80
Registration Number
NCT06218199
Locations
🇺🇸

Heart Center Research, LLC, Huntsville, Alabama, United States

Optimized Treatment of Pulmonary Edema or Congestion

First Posted Date
2022-03-11
Last Posted Date
2024-12-19
Lead Sponsor
Johannes Grand
Target Recruit Count
1104
Registration Number
NCT05276219
Locations
🇩🇰

Nordsjællands Hospital, Hillerød, Denmark

🇩🇰

Bispebjerg Hospital, Copenhagen, Denmark

🇩🇰

Hvidovre Hospital, Copenhagen, Denmark

and more 1 locations

Nitrate Effect on Exercise Capacitance

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-03-05
Last Posted Date
2021-09-22
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Target Recruit Count
20
Registration Number
NCT04297241
Locations
🇺🇸

Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio, United States

Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers

First Posted Date
2016-06-02
Last Posted Date
2021-01-12
Lead Sponsor
University of Guadalajara
Target Recruit Count
68
Registration Number
NCT02789033

Adequate Hydration Therapy Combined With Intravenous Infusion of Isosorbide Dinitrate Prevention for CIN

First Posted Date
2016-03-24
Last Posted Date
2016-03-24
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
400
Registration Number
NCT02718521
Locations
🇨🇳

Chinese People's Liberation Army General Hospital, Peking, Beijing, China

Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2016-01-08
Last Posted Date
2023-03-21
Lead Sponsor
Chinese University of Hong Kong
Registration Number
NCT02649998
Locations
🇭🇰

Prince of Wales Hospital, Sha Tin, NT, Hong Kong

Medical Management of Late Intrauterine Death.

First Posted Date
2015-07-02
Last Posted Date
2015-07-24
Lead Sponsor
National Institute of Perinatology
Target Recruit Count
60
Registration Number
NCT02488642

Non-inferiority of Pharmacological Prevention Alone Versus Pancreatic Stents to Prevent Post-ERCP Pancreatitis

First Posted Date
2015-02-23
Last Posted Date
2015-11-06
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
400
Registration Number
NCT02368795
Locations
🇮🇷

Shariati hospital, Tehran, Iran, Islamic Republic of

Nitrates In Combination With Hydralazine in cardiorEnal Syndrome (NICHE) Study

First Posted Date
2015-01-22
Last Posted Date
2015-01-22
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
100
Registration Number
NCT02343393
Locations
🇸🇬

Changi General Hospital, Singapore, Singapore

🇸🇬

National Heart Centre Singapore, Singapore, Singapore

🇸🇬

National University Hospital, Singapore, Singapore, Singapore

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