Acetazolamide
- Generic Name
- Acetazolamide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C4H6N4O3S2
- CAS Number
- 59-66-5
- Unique Ingredient Identifier
- O3FX965V0I
- Background
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of...
- Indication
For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma
- Associated Conditions
- Acute angle-closure glaucoma, Edema, Familial periodic paralysis, Generalized Tonic-Clonic Seizures, Metabolic Alkalosis, Open Angle Glaucoma (OAG), Other and unspecified effects of high altitude, Cystine renal calculi, Drug-induced edema, Nonuveitic secondary glaucoma, Salicylate intoxication
- Associated Therapies
- Urine alkalinization therapy
Sleep Apnea in Elderly
- Conditions
- Interventions
- First Posted Date
- 2016-03-09
- Last Posted Date
- 2024-07-17
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 100
- Registration Number
- NCT02703220
- Locations
- 🇺🇸
John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan, United States
A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing
- First Posted Date
- 2016-02-01
- Last Posted Date
- 2017-01-24
- Lead Sponsor
- NYU Langone Health
- Registration Number
- NCT02670096
- Locations
- 🇺🇸
New York University School of Medicine, New York, New York, United States
Altitude Sickness Prevention and Efficacy of Comparative Treatments
- Conditions
- Interventions
- First Posted Date
- 2015-11-13
- Last Posted Date
- 2018-12-12
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 103
- Registration Number
- NCT02604173
- Locations
- 🇺🇸
Owens Valley Lodge - White Mountain Research Station, Bishop, California, United States
Augmenting Cerebral Blood Flow to Treat Established Multiple Sclerosis
- First Posted Date
- 2015-06-09
- Last Posted Date
- 2023-04-27
- Target Recruit Count
- 5
- Registration Number
- NCT02466074
- Locations
- 🇺🇸
UTHealth, Houston, Texas, United States
Stop Retinal Ganglion Cell Dysfunction Study
- Conditions
- Interventions
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 500
- Registration Number
- NCT02390284
- Locations
- 🇺🇸
Bascom Palmer Eye Institute - University of Miami, Miami, Florida, United States
Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
- Conditions
- Interventions
- First Posted Date
- 2014-10-28
- Last Posted Date
- 2017-02-10
- Lead Sponsor
- Georgetown University
- Registration Number
- NCT02276989
- Locations
- 🇺🇸
Georgetown University, Washington, District of Columbia, United States
A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2014-08-20
- Last Posted Date
- 2016-08-16
- Lead Sponsor
- Göteborg University
- Target Recruit Count
- 13
- Registration Number
- NCT02220803
- Locations
- 🇸🇪
Center for Sleep and Vigilance disorders, Gothenburg, Vastra Gotaland, Sweden
Carbonic Anhydrase Antagonism in Subarachnoid Hemorrhage
- Conditions
- Interventions
- First Posted Date
- 2014-06-17
- Last Posted Date
- 2015-09-24
- Lead Sponsor
- University of Florida
- Registration Number
- NCT02165644
Normal Pressure Hydrocephalus Treatment by Acetazolamide
- Conditions
- Interventions
- First Posted Date
- 2014-06-13
- Last Posted Date
- 2017-04-13
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 2
- Registration Number
- NCT02163330
- Locations
- 🇮🇱
Rabin Medical Center, Petach Tiqva, Hamerkaz, Israel
Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection
- Conditions
- Interventions
- First Posted Date
- 2014-05-16
- Last Posted Date
- 2014-05-16
- Lead Sponsor
- Mashhad University of Medical Sciences
- Target Recruit Count
- 70
- Registration Number
- NCT02140450
- Locations
- 🇮🇷
Retina Research Center, Khatam eye Hospital, Mashhad, Khorasan Razavi, Iran, Islamic Republic of
Drug Development Updates
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