MedPath

Iclepertin

Generic Name
Iclepertin

A Study in Healthy People to Test Whether Iclepertin Has an Effect on Cardiac Safety

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2023-10-06
Last Posted Date
2024-07-09
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
56
Registration Number
NCT06070597
Locations
🇩🇪

CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany

A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2023-02-13
Last Posted Date
2023-06-06
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
14
Registration Number
NCT05723874
Locations
🇩🇪

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems

Phase 1
Completed
Conditions
Renal Insufficiency
Interventions
First Posted Date
2023-02-08
Last Posted Date
2023-11-18
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
36
Registration Number
NCT05718843
Locations
🇩🇪

CRS Clinical Research Services Kiel GmbH, Kiel, Germany

A Study in Healthy Women to Test Whether BI 425809 Influences the Amount of a Contraceptive in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Microgynon®
First Posted Date
2022-11-14
Last Posted Date
2023-10-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
19
Registration Number
NCT05613777
Locations
🇩🇪

CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany

A Study in Healthy People to Test How BI 425809 is Taken up in the Body When Taken With or Without Food

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-04-26
Last Posted Date
2023-01-04
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
16
Registration Number
NCT05347004
Locations
🇩🇪

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

A Study in Healthy Men to Test Whether BI 425809 Influences the Amount of Midazolam in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-02-28
Last Posted Date
2022-06-03
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
15
Registration Number
NCT05258110
Locations
🇩🇪

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study

Phase 3
Terminated
Conditions
Schizophrenia
Interventions
First Posted Date
2022-01-27
Last Posted Date
2025-04-27
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
1362
Registration Number
NCT05211947
Locations
🇬🇷

AX Mental Health Clinic, Heraclion, Greece

🇯🇵

Hokuriku Hospital, Toyama, Nanto, Japan

🇯🇵

Yamaguchi University Hospital, Yamaguchi, Ube, Japan

and more 300 locations

A Study in Healthy Men to Test How Fluconazole Influences the Amount of BI 425809 in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2021-10-13
Last Posted Date
2022-01-12
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
15
Registration Number
NCT05076409
Locations
🇩🇪

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

CONNEX-3: A Study to Test Whether Iclepertin Improves Learning and Memory in People With Schizophrenia

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2021-04-27
Last Posted Date
2025-01-09
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
609
Registration Number
NCT04860830
Locations
🇺🇸

Sunwise Clinical Research-Walnut Creek-70166, Walnut Creek, California, United States

🇺🇸

Synexus Clinical Research-Atlanta-67262, Atlanta, Georgia, United States

🇺🇸

Hassman Research Institute-Berlin-60540, Berlin, New Jersey, United States

and more 107 locations

Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-2)

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2021-04-15
Last Posted Date
2024-12-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
611
Registration Number
NCT04846881
Locations
🇺🇸

Research in Miami Inc, Hialeah, Florida, United States

🇺🇸

Salem VA Medical Center, Salem, Virginia, United States

🇪🇸

Benito Menni Complejo Asistencial en Salud Mental, Sant Boi de Llobregat, Spain

and more 124 locations
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