Cyproheptadine

Generic Name
Cyproheptadine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H21N
CAS Number
129-03-3
Unique Ingredient Identifier
2YHB6175DO
Background

Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.

Indication

In the US, prescription cyproheptadine is indicated for the treatment of various allergic symptomatologies - including dermatographia, rhinitis, conjunctivitis, and urticaria - as well as adjunctive therapy in the management of anaphylaxis following treatment with epinephrine. In Canada, cyproheptadine is available over-the-counter and is indicated for the t...

Associated Conditions
Allergic Reactions caused by Transfusions, Anaphylaxis, Angioedema and urticaria, Cold urticaria, Conjunctivitis allergic caused by Food Allergy, Conjunctivitis allergic caused by inhalant allergens, Perennial Allergic Rhinitis (PAR), Pruritus, Seasonal Allergic Rhinitis, Serotonin Syndrome, Vasomotor Rhinitis, Dermatographism
Associated Therapies
Appetite stimulation
Clinical Trials
Related News

Cyproheptadine as an Appetite Stimulant

First Posted Date
2011-03-15
Last Posted Date
2011-03-15
Lead Sponsor
St. Justine's Hospital
Target Recruit Count
20
Registration Number
NCT01314989
Locations
🇨🇦

Ste-Justine University Health Center, Montreal, Quebec, Canada

A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking

Phase 2
Completed
Conditions
Alcoholism
Interventions
Drug: Baclofen
Drug: Cyproheptadine
First Posted Date
2010-02-26
Last Posted Date
2013-10-17
Lead Sponsor
Brown University
Target Recruit Count
14
Registration Number
NCT01076283
Locations
🇺🇸

Brown University Center for Alcohol and Addiction Studies, Providence, Rhode Island, United States

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