Menotropins

Generic Name: Menotropins

Brand Names: Menopur

Drug Type: Biotech

CAS Number: 9002-68-0

Unique Ingredient Identifier: 8FYM5179QJ

Background: Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.

Indication: For the treatment of female infertility

Associated Therapies: Assisted Reproductive Technology therapy

Clinical Trials

Role of Aromatase Inhibitor to Enhance Ovulation in Poor Responder During Induction With Short Antagonist Protocol in Cases of ICSI

Phase 4

Completed

Conditions: Infertility Indicated for ICSI

Interventions: Drug: induction with aromataze inhibitor
Drug: HMG
Drug: GnRh a
Drug: HCG

First Posted Date: 2016-04-18

Last Posted Date: 2017-09-06

Lead Sponsor: Minia University

Target Recruit Count: 50

Registration Number: NCT02741154

Locations: 🇪🇬
Minia University, Minia, Egypt

Miniflare Versus Long Protocol in Poor Responders

Not Applicable

Conditions: Infertility

Interventions: Drug: Triptorelin
Drug: Combined oral contraceptive pills
Drug: HMG

First Posted Date: 2016-02-12

Last Posted Date: 2016-04-04

Lead Sponsor: Woman's Health University Hospital, Egypt

Target Recruit Count: 200

Registration Number: NCT02681536

Locations: 🇪🇬
Kasr el aini hospital, Cairo, Egypt

MENOPUR® in a Gonadotropin-Releasing Hormone (GnRH) Antagonist Cycle With Single-Blastocyst Transfer in a High Responder Subject Population

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: recombinant FSH
Drug: menotropin

First Posted Date: 2015-09-18

Last Posted Date: 2023-09-21

Lead Sponsor: Ferring Pharmaceuticals

Target Recruit Count: 620

Registration Number: NCT02554279

Locations: 🇺🇸
California Fertility Partners, Los Angeles, California, United States
🇺🇸
Houston Fertility Institute, Houston, Texas, United States
🇺🇸
Georgia Reproductive Specialists, Sandy Springs, Georgia, United States

and more 32 locations

Gonadotropin Type in Ovarian Stimulation

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: recombinant FSH
Drug: Urinary FSH
Drug: hMG

First Posted Date: 2015-05-07

Last Posted Date: 2015-05-07

Lead Sponsor: IVI Madrid

Target Recruit Count: 100

Registration Number: NCT02437032

Mono-menotropins Versus rFSH Protocol on Embryo Quality

Not Applicable

Completed

Conditions: Infertility
Fertility

Interventions: Drug: Recominant Follicle Stimulating Hormone (rFSH)
Drug: menotropin

First Posted Date: 2015-04-16

Last Posted Date: 2020-08-12

Lead Sponsor: Main Line Fertility Center

Target Recruit Count: 109

Registration Number: NCT02418533

Locations: 🇺🇸
Main Line Fertility Center, Bryn Mawr, Pennsylvania, United States

Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: rFSH
Drug: HMG

First Posted Date: 2015-04-09

Last Posted Date: 2015-08-21

Lead Sponsor: Hospital de Clinicas de Porto Alegre

Target Recruit Count: 188

Registration Number: NCT02412904

Locations: 🇧🇷
Centro de Reproduçao Humana Insemine, Porto Alegre, RGS, Brazil

Ovarian Stimulation With Recombinant Gonadotropins vs. Human Menopausal Gonadotropin in In Vitro Fertilization

Completed

Conditions: Infertility

Interventions: Drug: rFSH plus rLH
Drug: hMG

First Posted Date: 2014-12-23

Last Posted Date: 2014-12-23

Lead Sponsor: University of Turin, Italy

Target Recruit Count: 848

Registration Number: NCT02322398

Locations: 🇮🇹
Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Torino, Italy

Use of Corifolitropin Alfa in Oocyte Donors

Phase 4

Conditions: Female Reproductive Problem
Infertility

Interventions: Drug: Corifollitropin alfa
Drug: Recombinant FSH
Drug: HP-hMG

First Posted Date: 2014-08-11

Last Posted Date: 2015-07-17

Lead Sponsor: IVI Madrid

Target Recruit Count: 300

Registration Number: NCT02213627

Locations: 🇪🇸
IVI Madrid, Madrid, Spain

Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation

Phase 4

Completed

Conditions: Egg Donation

Interventions: Drug: Follistim
Drug: Ganirelix
Drug: Menotropins
Drug: Leuprolide
Procedure: Transvaginal ultrasound guided needle aspiration of oocytes

First Posted Date: 2014-02-24

Last Posted Date: 2018-03-23

Lead Sponsor: Michigan Reproductive Medicine

Target Recruit Count: 38

Registration Number: NCT02069808

Locations: 🇺🇸
Michigan Reproductive Medicine, Bloomfield Hills, Michigan, United States

An Explorative Prospective Observational Study to Describe Morphokinetic De-selection Parameters in Human Embryos

Completed

Conditions: Infertility

Interventions: Drug: menotropin

First Posted Date: 2013-12-23

Last Posted Date: 2017-08-28

Lead Sponsor: Ferring Pharmaceuticals

Target Recruit Count: 738

Registration Number: NCT02018159

Locations: 🇩🇰
Fertilitetsklinikken Hospitalsenheden Horsens, Regionshospitalet Horsens (there may be other sites in this country), Horsens, Denmark

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