Cilostazol

Generic Name
Cilostazol
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H27N5O2
CAS Number
73963-72-1
Unique Ingredient Identifier
N7Z035406B
Background

Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reduci...

Indication

Indicated for the alleviation of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).

Associated Conditions
Intermittent Claudication
Associated Therapies
-

Triple Versus Dual Antiplatelet Therapy in Patients Undergoing Coronary Stent Implantation

Phase 4
Completed
Conditions
First Posted Date
2006-11-29
Last Posted Date
2006-11-29
Lead Sponsor
Shenyang Northern Hospital
Registration Number
NCT00404716

The Use of Cilostazol in Patients With Diabetic Nephropathy

First Posted Date
2006-01-09
Last Posted Date
2009-05-22
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
62
Registration Number
NCT00272831

Cilostazol in Acute Ischemic Stroke Treatment (CAIST)

Phase 4
Completed
Conditions
First Posted Date
2006-01-06
Last Posted Date
2009-12-16
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
468
Registration Number
NCT00272454
Locations
🇰🇷

Hallym University Sacred Heart Hospital, Ahnyang, Kyunggi Province, Korea, Republic of

🇰🇷

Inje University Ilsan Paik Hospital, Koyang, Kyunggi Province, Korea, Republic of

🇰🇷

Seoul National University Bundang Hospital, Sungnam, Kyunggi Province, Korea, Republic of

and more 8 locations

Post-marketing Study of Cilostazol (Cilostazol Stroke Prevention Study 2)

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-10-06
Last Posted Date
2011-06-10
Lead Sponsor
Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
2800
Registration Number
NCT00234065
Locations
🇯🇵

Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan

Claudication: Exercise Versus Endoluminal Revascularization (CLEVER)

First Posted Date
2005-08-22
Last Posted Date
2013-04-25
Lead Sponsor
Joselyn Cerezo, MD
Target Recruit Count
119
Registration Number
NCT00132743
Locations
🇺🇸

Rapides Regional Medical Center, Alexandria, Louisiana, United States

🇺🇸

VA Palo Alto Health Care Systems, Palo Alto, California, United States

🇺🇸

The Iowa Clinic, Des Moines, Iowa, United States

and more 24 locations

Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II

First Posted Date
2005-08-15
Last Posted Date
2010-01-12
Lead Sponsor
Asan Medical Center
Target Recruit Count
457
Registration Number
NCT00130039
Locations
🇰🇷

Inje University Ilsan Paik Hospital, Goyang, Gyeonggi-do, Korea, Republic of

🇰🇷

Dongguk University International Hospital, Goyang, Kyoungki-do, Korea, Republic of

🇰🇷

Hallym University Sacred Heart Hospital, Anyang, Kyunggi, Korea, Republic of

and more 16 locations

Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon

Phase 4
Completed
Conditions
First Posted Date
2002-11-11
Last Posted Date
2005-07-19
Lead Sponsor
Otsuka America Pharmaceutical
Target Recruit Count
75
Registration Number
NCT00048763
Locations
🇺🇸

The Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

🇺🇸

LaRabida Children's Hospital, Chicago, Illinois, United States

🇺🇸

Advanced Medical Clinical Therapeutics, Anchorage, Alaska, United States

and more 15 locations

Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon

Phase 4
Completed
Conditions
First Posted Date
2002-11-11
Last Posted Date
2005-07-19
Lead Sponsor
Otsuka America Pharmaceutical
Target Recruit Count
75
Registration Number
NCT00048776
Locations
🇺🇸

Madera Family Medical Group, Madera, California, United States

🇺🇸

Children's Hospital Boston, Boston, Massachusetts, United States

🇺🇸

St. Louis University Health Sciences Center, St. Louis, Missouri, United States

and more 16 locations
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