Cilostazol

Generic Name
Cilostazol
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H27N5O2
CAS Number
73963-72-1
Unique Ingredient Identifier
N7Z035406B
Background

Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reduci...

Indication

Indicated for the alleviation of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).

Associated Conditions
Intermittent Claudication
Associated Therapies
-

Effect of Cilostazol on Endothelial Progenitor Cells and Endothelial Function in Coronary Artery Disease

First Posted Date
2014-06-26
Last Posted Date
2015-10-14
Lead Sponsor
National Cheng-Kung University Hospital
Target Recruit Count
300
Registration Number
NCT02174939
Locations
🇨🇳

National Cheng Kung University Hospital, Tainan, Taiwan

Safety and Efficacy Study of Cilostazol to Treat Vasospastic Angina

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-03-21
Last Posted Date
2016-01-29
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
65
Registration Number
NCT02094469
Locations
🇰🇷

Yangsan Busan University Hospital, Busan, Korea, Republic of

A Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Cilostazol in Subjects With Vasospastic Angina

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-03-14
Last Posted Date
2017-05-04
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
100
Registration Number
NCT02087007
Locations
🇰🇷

Yangsan Busan University Hospital, Busan, Korea, Republic of

Cilostazol Stroke Prevention Study for Antiplatelet Combination

First Posted Date
2013-11-26
Last Posted Date
2019-03-28
Lead Sponsor
Japan Cardiovascular Research Foundation
Target Recruit Count
1884
Registration Number
NCT01995370
Locations
🇯🇵

Japan Cardiovascular Research Foundation, Osaka, Japan

OPTImal Management of Antithrombotic Agents: OPTIMA-2 Trial

First Posted Date
2013-10-07
Last Posted Date
2020-08-18
Lead Sponsor
The First Affiliated Hospital with Nanjing Medical University
Target Recruit Count
1724
Registration Number
NCT01955200
Locations
🇨🇳

First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Effect of Cilostazol Endothelial Progenitor Cells and Collateral Formation in Peripheral Occlusive Artery Disease (PAOD)

First Posted Date
2013-09-30
Last Posted Date
2014-07-18
Lead Sponsor
National Cheng-Kung University Hospital
Target Recruit Count
44
Registration Number
NCT01952756
Locations
🇨🇳

National Cheng Kung University Hospital, Tainan, Taiwan

Efficacy Study of Cilostazol and Aspirin on Cerebral Small Vessel Disease

First Posted Date
2013-08-30
Last Posted Date
2019-08-08
Lead Sponsor
Inha University Hospital
Target Recruit Count
255
Registration Number
NCT01932203
Locations
🇰🇷

Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong-si, Gyeonggi-do, Korea, Republic of

🇰🇷

Hallym University Medical Center, Anyang, Korea, Republic of

🇰🇷

Eulji University School of Medicine, Daejeon, Korea, Republic of

and more 16 locations

Cilostazol and Its Effects on Resumption of Meiosis in the Human Ovary

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-08-02
Last Posted Date
2015-05-12
Lead Sponsor
University of Southern California
Target Recruit Count
4
Registration Number
NCT01915069
Locations
🇺🇸

University of Southern California Fertility Clinic, Los Angeles, California, United States

Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)

Not Applicable
Conditions
Interventions
First Posted Date
2013-06-07
Last Posted Date
2013-06-07
Lead Sponsor
Huashan Hospital
Target Recruit Count
200
Registration Number
NCT01872858
Locations
🇨🇳

Dept. of Neurology, Huashan Hospital, Fudan University, Shanghai, Shanghai, China

Pharmacodynamic Drug Interaction Between Cilostazol and Statins

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-06-06
Last Posted Date
2015-05-27
Lead Sponsor
Samsung Medical Center
Target Recruit Count
63
Registration Number
NCT01870466
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

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