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LY-3023414

Generic Name
LY-3023414
Drug Type
Small Molecule
Chemical Formula
C23H26N4O3
CAS Number
1386874-06-1
Unique Ingredient Identifier
C88817F47Y
Background

LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.

A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer

Phase 1
Completed
Conditions
Breast Cancer
Neoplasm Metastasis
Colorectal Neoplasms
Interventions
First Posted Date
2014-04-28
Last Posted Date
2020-04-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
167
Registration Number
NCT02124148
Locations
🇺🇸

Sarah Cannon Research Institute SCRI, Nashville, Tennessee, United States

🇺🇸

Tennessee Oncology PLLC, Nashville, Tennessee, United States

🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

and more 2 locations

A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)

Phase 1
Completed
Conditions
Carcinoma, Non-small Cell Lung
Interventions
First Posted Date
2014-03-06
Last Posted Date
2020-09-11
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
142
Registration Number
NCT02079636
Locations
🇺🇸

Highlands Oncology Group, Fayetteville, Arkansas, United States

🇺🇸

Indiana Cancer Pavilion, Indianapolis, Indiana, United States

🇺🇸

The West Clinic, Germantown, Tennessee, United States

and more 7 locations

A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

First Posted Date
2014-02-06
Last Posted Date
2025-04-20
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
198
Registration Number
NCT02057133
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Highlands Oncology Group - Duplicate 2, Rogers, Arkansas, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

and more 10 locations

A Study of LY3023414 in Participants With Advanced Cancer

Phase 1
Completed
Conditions
Metastatic Breast Cancer
Non-small Cell Lung Cancer
Malignant Mesothelioma
Advanced Cancer
Metastatic Cancer
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2012-08-01
Last Posted Date
2022-04-08
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
156
Registration Number
NCT01655225
Locations
🇺🇸

UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States

🇮🇹

Azienda Ospedaliero - Universitaria S. Luigi Gonzaga, Orbassano, Torino, Italy

and more 5 locations
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