Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
Phase 2
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-05-13
- Last Posted Date
- 2024-05-13
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Target Recruit Count
- 78
- Registration Number
- NCT06411795
- Locations
- 🇺🇸
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, United States
Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block
- First Posted Date
- 2024-04-26
- Last Posted Date
- 2024-05-03
- Lead Sponsor
- Aswan University
- Target Recruit Count
- 75
- Registration Number
- NCT06386770
- Locations
- 🇪🇬
Aswan University, Aswan, Egypt
Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion
Phase 2
- Conditions
- Interventions
- First Posted Date
- 2024-04-08
- Last Posted Date
- 2024-06-13
- Target Recruit Count
- 76
- Registration Number
- NCT06350981
- Locations
- 🇺🇸
Foundation for Orthopaedic Research and Education, Tampa, Florida, United States
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
Early Phase 1
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-04-05
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- Texas Tech University Health Sciences Center
- Target Recruit Count
- 130
- Registration Number
- NCT06349772
Impact of Opioid Avoidance Protocol for ACL Reconstruction
- First Posted Date
- 2024-04-02
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Matthew Varacallo
- Target Recruit Count
- 40
- Registration Number
- NCT06340932
- Locations
- 🇺🇸
Penn Highlands Dubois, DuBois, Pennsylvania, United States
Short Title: Standard vs. Lower Pressure Pneumoperitoneum
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-04-01
- Last Posted Date
- 2024-05-10
- Lead Sponsor
- Cedars-Sinai Medical Center
- Target Recruit Count
- 294
- Registration Number
- NCT06338865
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-03-26
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 40
- Registration Number
- NCT06331182
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbia, Egypt
Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-03-04
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- South Valley University
- Target Recruit Count
- 60
- Registration Number
- NCT06290583
Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA
Phase 4
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-03-04
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- Prisma Health-Upstate
- Target Recruit Count
- 138
- Registration Number
- NCT06291727
- Locations
- 🇺🇸
Prisma Health Patewood Hospital, Greenville, South Carolina, United States
Epidural Oxycodone for Pain Management for Lower Limb Amputation
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-02-23
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 40
- Registration Number
- NCT06276179
- Locations
- 🇪🇬
Kafrelsheikh University, Kafr Ash Shaykh, Kafrelsheikh, Egypt
Drug Development Updates
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