Riboflavin
- Generic Name
- Riboflavin
- Brand Names
- Alertonic, Concept Ob, Irospan 24/6 Kit, Mvc-fluoride, Natafort, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C17H20N4O6
- CAS Number
- 83-88-5
- Unique Ingredient Identifier
- TLM2976OFR
- Background
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
- Indication
For the treatment of ariboflavinosis (vitamin B2 deficiency).
- Associated Conditions
- Ariboflavinosis, Beriberi, Constipation, Functional Gastrointestinal Disorders (FGID), Joint Pain, Metabolic cardiomyopathy, Migraine, Myalgia, Neuropathic Pain, Peripheral neuritis, Peripheral paralysis, Vitamin B complex deficiency, Vitamin B1 deficiency, Vitamin Deficiency, Wernicke's encephalopathy
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation, Vitamin supplementation, Dietary supplementation
Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure
- First Posted Date
- 2018-06-11
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 100
- Registration Number
- NCT03552016
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
- Conditions
- Ureteral Injury
- Interventions
- First Posted Date
- 2018-02-14
- Last Posted Date
- 2020-08-11
- Lead Sponsor
- Texas Tech University Health Sciences Center
- Target Recruit Count
- 120
- Registration Number
- NCT03432572
- Locations
- 🇺🇸
Texas Tech University Health Sciences Center, Lubbock, Texas, United States
Accelerated Corneal Cross-linking With Different Riboflavin Solutions
- First Posted Date
- 2017-06-15
- Last Posted Date
- 2021-03-03
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 60
- Registration Number
- NCT03187912
- Locations
- 🇦🇹
Medical University of Vienna, Department of Ophthalmology, Vienna, Austria
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
- Conditions
- OsteomyelitisDiabetesAmputation
- Interventions
- First Posted Date
- 2017-01-06
- Last Posted Date
- 2025-05-16
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 880
- Registration Number
- NCT03012529
- Locations
- 🇺🇸
Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona, United States
🇺🇸VA Loma Linda Healthcare System, Loma Linda, CA, Loma Linda, California, United States
🇺🇸VA Long Beach Healthcare System, Long Beach, CA, Long Beach, California, United States
Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL).
- Conditions
- KeratoconusCorneal Ectasia
- Interventions
- Device: UV-X 1000 (3 mW/cm²)Procedure: UV-X 2000 (9 mW/cm²)
- First Posted Date
- 2016-08-30
- Last Posted Date
- 2016-08-30
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT02883478
Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit
- Conditions
- Keratolysis
- Interventions
- First Posted Date
- 2016-08-11
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Joseph B. Ciolino, MD
- Target Recruit Count
- 76
- Registration Number
- NCT02863809
- Locations
- 🇺🇸
UC Davis Health System Eye Center, Sacramento, California, United States
🇺🇸The Jules Stein Eye Institute, Los Angeles, California, United States
🇺🇸Shiley Eye Institute, University of California, San Diego, San Diego, California, United States
The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral Ulcer
- Conditions
- Crohn's DiseaseOral Ulcer
- Interventions
- First Posted Date
- 2016-05-11
- Last Posted Date
- 2023-02-01
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Registration Number
- NCT02769494
- Locations
- 🇨🇳
Xijing Hospital, Xi'an, Shaanxi, China
Study of the Safety and Effectiveness of Photochemically Induced Collagen Cross-Linking in Eyes With Keratoconus.
- First Posted Date
- 2016-05-04
- Last Posted Date
- 2016-05-05
- Lead Sponsor
- Nvision Laser Eye Centers
- Target Recruit Count
- 320
- Registration Number
- NCT02762253
- Locations
- 🇺🇸
NVISION Fullerton, Fullerton, California, United States
🇺🇸NVISION Laguna Hills, Laguna Hills, California, United States
🇺🇸NVISION Las Vegas, Las Vegas, Nevada, United States
The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
- First Posted Date
- 2015-12-04
- Last Posted Date
- 2022-07-28
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 23
- Registration Number
- NCT02622386
- Locations
- 🇺🇸
University of Michigan Department of Dermatology, Ann Arbor, Michigan, United States
Treatment of Keratoconus With Advanced CXL-II
- Conditions
- Keratoconus
- Interventions
- Procedure: Topography-based CXL (KXL2)Procedure: Conventional pulsed CXL (pCXL)Device: Avedro KXL II
- First Posted Date
- 2015-08-03
- Last Posted Date
- 2018-05-16
- Lead Sponsor
- Umeå University
- Target Recruit Count
- 50
- Registration Number
- NCT02514200
Drug Development Updates
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