Canrenoic acid
- Generic Name
- Canrenoic acid
- Drug Type
- Small Molecule
- Chemical Formula
- C22H30O4
- CAS Number
- 4138-96-9
- Unique Ingredient Identifier
- 87UG89VA9K
- Background
Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
- Associated Conditions
- Edema, Edema caused by Secondary aldosteronism, Essential Arterial Hypertension, Hypertension, Primary Hyperaldosteronism
Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment
Phase 4
Completed
- Conditions
- Acute Heart FailureDiuretics Drug Reactions
- Interventions
- Diagnostic Test: UNa measurement after intravenous loop diuretic bolusOther: Usual AHF careOther: Maintenance infusionOther: Intravenous hypertonic salineOther: Switch to oral diuretic therapy
- First Posted Date
- 2022-06-09
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Vrije Universiteit Brussel
- Target Recruit Count
- 107
- Registration Number
- NCT05411991
- Locations
- 🇧🇪
Jessa Hospital, Hasselt, Limburg, Belgium
🇧🇪University Hospital Brussels, Jette, Brussels, Belgium
Mineralocorticoid Receptor Antagonist and Pulmonary Fibrosis in COVID-19.
- First Posted Date
- 2021-06-03
- Last Posted Date
- 2021-06-08
- Lead Sponsor
- Pomeranian Medical University Szczecin
- Target Recruit Count
- 50
- Registration Number
- NCT04912011
- Locations
- 🇵🇱
Pomeranian Medical University, Szczecin, Poland
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