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Pancrelipase protease

Generic Name
Pancrelipase protease
Brand Names
Cotazym, Creon, Pancrease MT, Pancreaze, Pertzye, Viokace, Zenpep
Drug Type
Biotech
CAS Number
9001-94-9
Unique Ingredient Identifier
3560D81V50

Overview

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase protease is a mix of enzymes, formed by trypsin and chymotrypsin, that proteolytically cleave peptide bonds and are involved in food digestion. The pancrelipase mixture, including pancrelipase protease, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.

Background

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase protease is a mix of enzymes, formed by trypsin and chymotrypsin, that proteolytically cleave peptide bonds and are involved in food digestion. The pancrelipase mixture, including pancrelipase protease, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.

Indication

Please refer to Pancrelipase.

Associated Conditions

  • Exocrine Pancreatic Insufficiency

FDA Approved Products

Zenpep
Manufacturer:Aimmune Therapeutics, Inc.
Route:ORAL
Strength:189600 [USP'U] in 1 1
Approved: 2023/10/27
NDC:73562-117
Zenpep
Manufacturer:Aimmune Therapeutics, Inc.
Route:ORAL
Strength:47000 [USP'U] in 1 1
Approved: 2023/10/27
NDC:73562-111
ZENPEP
Manufacturer:Physicians Total Care, Inc.
Route:ORAL
Strength:34000 [USP'U] in 1 1
Approved: 2014/09/15
NDC:54868-6435
Creon
Manufacturer:AbbVie Inc.
Route:ORAL
Strength:114000 [USP'U] in 1 1
Approved: 2024/03/06
NDC:0032-3016
Creon
Manufacturer:AbbVie Inc.
Route:ORAL
Strength:9500 [USP'U] in 1 1
Approved: 2024/03/06
NDC:0032-1203

Singapore Approved Products

ENZYPLEX TABLET
Manufacturer:PT MEDIFARMA LABORATORIES INC
Form:ENTERIC COATED TABLET
Strength:9000 u
Online:Yes
Approved: 1991/05/03
Approval:SIN06211P

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