MedPath

Cefazolin

Generic Name
Cefazolin
Drug Type
Small Molecule
Chemical Formula
C14H14N8O4S3
CAS Number
25953-19-9
Unique Ingredient Identifier
IHS69L0Y4T

Overview

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Background

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Indication

Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis; if required metronidazole may be added to cover B. fragilis.

Associated Conditions

  • Bacterial Septicemia caused by susceptible Bacterial Infections
  • Biliary tract infection bacterial caused by susceptible Bacterial Infections
  • Bone and Joint Infections caused by susceptible Bacterial Infections
  • Catheter-related Bloodstream Infection (CRBSI) NOS
  • Community Acquired Pneumonia (CAP)
  • Endocarditis caused by susceptible Bacterial Infections
  • Genital infection caused by susceptible Bacterial Infections
  • Osteoarticular Infections
  • Postoperative Infections
  • Respiratory Tract Infection Bacterial caused by susceptible Bacterial Infections
  • Skin and Soft Tissue Infections (SSTIs)
  • Skin and Subcutaneous Tissue Infection caused by susceptible Bacterial Infections
  • Susceptible infections
  • Urinary Tract Infection caused by susceptible Bacterial Infections
  • Perioperative infection
  • Susceptible Bacterial Infections

FDA Approved Products

Cefazolin
Manufacturer:Medical Purchasing Solutions, LLC
Route:INTRAVENOUS, INTRAMUSCULAR
Strength:1 g in 1 1
Approved: 2023/05/16
NDC:71872-7141
CEFAZOLIN
Manufacturer:Samson Medical Technologies, L.L.C.
Route:INTRAVENOUS
Strength:300 g in 1 1
Approved: 2018/10/24
NDC:66288-1300
CEFAZOLIN
Manufacturer:Samson Medical Technologies, L.L.C.
Route:INTRAVENOUS
Strength:100 g in 1 1
Approved: 2018/10/24
NDC:66288-1100
Cefazolin Sodium
Manufacturer:Cantrell Drug Company
Route:INTRAVENOUS
Strength:30 mg in 1 mL
Approved: 2013/12/05
NDC:52533-113
Cefazolin
Manufacturer:Apotex Corp.
Route:INTRAMUSCULAR, INTRAVENOUS
Strength:3 g in 1 1
Approved: 2024/02/18
NDC:60505-6266

Singapore Approved Products

Zepilen Powder for Injection 1g/vial
Manufacturer:Medochemie Ltd - Factory C, MEDOCHEMIE (FAR EAST) LTD., (ASEPTIC CEPHALOSPORIN FACILITY)
Form:INJECTION, POWDER, FOR SOLUTION
Strength:1000 mg
Online:Yes
Approved: 2013/01/31
Approval:SIN14304P
CEFAZOLIN-AFT POWDER FOR INJECTION 500MG/VIAL
Manufacturer:Qilu Pharmaceuticals Co. Ltd
Form:INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Strength:500MG
Online:Yes
Approved: 2016/05/25
Approval:SIN15018P
CEFAZOLIN-AFT POWDER FOR INJECTION 1G/VIAL
Manufacturer:QILU PHARMACEUTICAL CO., LTD
Form:INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Strength:1 g/vial
Online:Yes
Approved: 2014/01/13
Approval:SIN14480P
CEZOLIN INJECTION 1 gm/vial
Manufacturer:DAE HAN NEW PHARM. CO. LTD.
Form:INJECTION, POWDER, FOR SOLUTION
Strength:1 gm/vial
Online:Yes
Approved: 2003/12/05
Approval:SIN12471P
CEFAZOLIN ALVOGEN POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL
Manufacturer:Sinopharm Zhijun (Shenzhen) Pharmaceutical Co., Ltd
Form:INJECTION, POWDER, FOR SOLUTION
Strength:1 g
Online:Yes
Approved: 2015/09/16
Approval:SIN14846P

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