Epinastine

Generic Name
Epinastine
Brand Names
Elestat
Drug Type
Small Molecule
Chemical Formula
C16H15N3
CAS Number
80012-43-7
Unique Ingredient Identifier
Q13WX941EF
Background

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to stop itching and provide lastin...

Indication

For the prevention of itching associated with allergic conjunctivitis.

Associated Conditions
Allergic Conjunctivitis (AC)
Associated Therapies
-

Epinastine + Pseudoephedrine SR (Slow Release) Versus Epinastine Alone in Patients With Perennial Allergic Rhinitis

First Posted Date
2014-07-08
Last Posted Date
2014-07-14
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
101
Registration Number
NCT02182518

Epinastine and Pseudoephedrine Fixed Combination Compared to Separate Administration in Healthy Volunteers

First Posted Date
2014-07-08
Last Posted Date
2014-07-14
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
25
Registration Number
NCT02182531

Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-09-26
Last Posted Date
2015-05-13
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
79
Registration Number
NCT00534794
Locations
🇺🇸

Ophthalmic Consultants of Boston, Boston, Massachusetts, United States

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