Polyethylene glycol

Generic Name
Polyethylene glycol
Brand Names
Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
25322-68-3
Unique Ingredient Identifier
3WJQ0SDW1A
Background

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...

Indication

Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.

Associated Conditions
Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
Associated Therapies
Bowel preparation therapy, Eye lubrication

PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy

First Posted Date
2017-04-04
Last Posted Date
2017-04-27
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
100
Registration Number
NCT03100513
Locations
🇪🇬

Tropical medicine dept.-Tanta university hospital, Cairo, Egypt

To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation

First Posted Date
2017-02-23
Last Posted Date
2018-07-13
Lead Sponsor
AstraZeneca
Target Recruit Count
276
Registration Number
NCT03060512
Locations
🇺🇸

Research Site, West Jordan, Utah, United States

Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

First Posted Date
2016-05-06
Last Posted Date
2024-02-06
Lead Sponsor
University of Pennsylvania
Target Recruit Count
8
Registration Number
NCT02765256
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months

First Posted Date
2016-04-26
Last Posted Date
2020-05-29
Lead Sponsor
Aboca Spa Societa' Agricola
Target Recruit Count
158
Registration Number
NCT02751411
Locations
🇮🇹

ASL 1 Avezzano Sulmona L'Aquila - Ospedale San Salvatore - UO Clinica Pediatrica - Località Coppito, L'Aquila, AQ, Italy

🇮🇹

Fondazione IRCCS Policlinico San Matteo di Pavia- Dipartimento Scienze Clinico-Chirurgiche, Diagnostiche e Pediatriche - Viale Golgi, 19, Pavia, PV, Italy

🇮🇹

Dipartimento di Scienze Mediche Traslazionali - Pediatria - Università Federico II, Napoli, Italy

and more 1 locations

Mechanical Bowel Preparation for Elective Colorectal Anastomosis

Phase 3
Completed
Conditions
Interventions
First Posted Date
2016-04-08
Last Posted Date
2016-04-08
Lead Sponsor
Instituto Mexicano del Seguro Social
Target Recruit Count
81
Registration Number
NCT02731963
Locations
🇲🇽

Western Medical Center, Mexican Institute of Social Security, Guadalajara, Jalisco, Mexico

The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit

First Posted Date
2016-03-10
Last Posted Date
2021-05-05
Lead Sponsor
Massachusetts General Hospital
Registration Number
NCT02705378
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-09-23
Last Posted Date
2015-09-23
Lead Sponsor
Democritus University of Thrace
Target Recruit Count
80
Registration Number
NCT02558218
Locations
🇬🇷

Eye Institute Of thrace, Alexandroupolis, Evros, Greece

Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy

First Posted Date
2015-07-23
Last Posted Date
2016-03-18
Lead Sponsor
Changhai Hospital
Target Recruit Count
300
Registration Number
NCT02507037
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