Polyethylene glycol

Generic Name
Polyethylene glycol
Brand Names
Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
25322-68-3
Unique Ingredient Identifier
3WJQ0SDW1A
Background

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...

Indication

Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.

Associated Conditions
Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
Associated Therapies
Bowel preparation therapy, Eye lubrication

The Effect of Bowel Preparation on Perioperative Bleeding

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-07-10
Last Posted Date
2015-07-10
Lead Sponsor
Isfahan University of Medical Sciences
Target Recruit Count
105
Registration Number
NCT02493894
Locations
🇮🇷

Alzahra Hospital, Isfahan, Iran, Islamic Republic of

The Best Dosage and Timing of Polyethylene Glycol for Bowel Preparation Before Capsule Endoscopy

First Posted Date
2015-07-01
Last Posted Date
2017-06-22
Lead Sponsor
Zhizheng Ge
Target Recruit Count
410
Registration Number
NCT02486536
Locations
🇨🇳

Huashan Hospital, Shanghai, Shanghai, China

🇨🇳

Tongren Hospital Affiliated to Shanghai Jiaotong University, China, Shanghai, Shanghai, China

🇨🇳

Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure

First Posted Date
2015-06-25
Last Posted Date
2017-03-07
Lead Sponsor
Medtronic - MITG
Target Recruit Count
122
Registration Number
NCT02481219
Locations
🇺🇸

Franklin Gastroenterology, PLLC, Franklin, Tennessee, United States

🇺🇸

Indiana University Hospital, Indianapolis, Indiana, United States

🇺🇸

Pinnacle Research Group, LLC, Anniston, Alabama, United States

and more 3 locations

Intestinal Lavage for the Treatment of Severe C. Difficile Infections

First Posted Date
2015-06-09
Last Posted Date
2018-08-13
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
20
Registration Number
NCT02466698
Locations
🇨🇦

London Health Sciences Centre, London, Ontario, Canada

Pediatrics Anal Fissures Treatment With Polyethylene Glycol

First Posted Date
2015-04-17
Last Posted Date
2016-03-01
Lead Sponsor
King Saud University
Target Recruit Count
46
Registration Number
NCT02419534
Locations
🇸🇦

College of medicine, king saud university, Riyadh, Nejd Province - Central, Saudi Arabia

Split-dose Versus Single-dose Polyethylene Glycol Regimen for Capsule Endoscopy

First Posted Date
2015-03-24
Last Posted Date
2015-03-24
Lead Sponsor
Centro Hospitalar Lisboa Ocidental
Target Recruit Count
50
Registration Number
NCT02396017
Locations
🇵🇹

Gastroenterology Department, Hospital Egas Moniz, Lisboa, Portugal

Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction

First Posted Date
2015-01-13
Last Posted Date
2018-04-11
Lead Sponsor
Rabin Medical Center
Registration Number
NCT02336906
Locations
🇮🇱

Institute of Gastroenterology, Nutrition, and Liver Diseases; Schneider Children's Medical Center of Israel, Petach Tikva, Israel

Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis

First Posted Date
2015-01-13
Last Posted Date
2018-04-11
Lead Sponsor
Rabin Medical Center
Registration Number
NCT02337413
Locations
🇮🇱

Institute of Gastroenterology, Nutrition and Liver Diseases; Schneider Children's Medical Center of Israel, Petach Tikva, Israel

Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.

First Posted Date
2014-02-27
Last Posted Date
2016-06-27
Lead Sponsor
Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Target Recruit Count
472
Registration Number
NCT02073552
Locations
🇪🇸

Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain

Patient Tolerability and Efficacy of Bowel Preparation With Split Dose Picosalax vs. Split Dose PEG

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2014-02-25
Last Posted Date
2015-09-28
Lead Sponsor
Queen's University
Target Recruit Count
5
Registration Number
NCT02070341
Locations
🇨🇦

Hotel Dieu Hospital, Kingston, Ontario, Canada

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