Polyethylene glycol

Generic Name
Polyethylene glycol
Brand Names
Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
25322-68-3
Unique Ingredient Identifier
3WJQ0SDW1A
Background

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...

Indication

Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.

Associated Conditions
Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
Associated Therapies
Bowel preparation therapy, Eye lubrication

A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy

First Posted Date
2009-12-09
Last Posted Date
2012-03-14
Lead Sponsor
Southern California Institute for Research and Education
Target Recruit Count
400
Registration Number
NCT01028573
Locations
🇺🇸

VA Long Beach Healthcare System, Long Beach, California, United States

Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216)

First Posted Date
2008-10-10
Last Posted Date
2018-10-02
Lead Sponsor
Bayer
Target Recruit Count
203
Registration Number
NCT00770432

Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-10-03
Last Posted Date
2021-01-15
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
138
Registration Number
NCT00765557

Probiotics for Eradication of Carbapenem Resistant Klebsiella Pneumonia

First Posted Date
2008-07-25
Last Posted Date
2008-07-25
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
60
Registration Number
NCT00722410
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination

First Posted Date
2008-05-15
Last Posted Date
2015-09-25
Lead Sponsor
Queen's University
Target Recruit Count
198
Registration Number
NCT00677794
Locations
🇨🇦

Hotel Dieu Hospital, Kingston, Ontario, Canada

Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation

First Posted Date
2008-01-29
Last Posted Date
2008-10-07
Lead Sponsor
Orion Corporation, Orion Pharma
Target Recruit Count
67
Registration Number
NCT00603681
Locations
🇫🇮

Tampereen sotainvalidien Veljeskoti, Tampere, Finland

🇫🇮

Vire Koti Kaukaharju assisted-living facility, Tampere, Finland

🇫🇮

Taatala assested-living facility, Tampere, Finland

and more 7 locations

Polyethylene Glycol Versus Sodium Phosphate for Colon Preparation After Failure of First Preparation for Colonoscopy

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2007-11-14
Last Posted Date
2018-06-14
Lead Sponsor
Sheba Medical Center
Target Recruit Count
23
Registration Number
NCT00558376
Locations
🇮🇱

Sheba_Medical_Center, Tel-Hashomer, Israel

A Pilot Study of a New MiraLax® Dose Formulation For Use in Constipated Children

Phase 4
Completed
Conditions
First Posted Date
2006-04-27
Last Posted Date
2013-02-07
Lead Sponsor
Braintree Laboratories
Target Recruit Count
25
Registration Number
NCT00319670
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