Polyethylene glycol
- Generic Name
- Polyethylene glycol
- Brand Names
- Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 25322-68-3
- Unique Ingredient Identifier
- 3WJQ0SDW1A
- Background
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...
- Indication
Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.
- Associated Conditions
- Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
- Associated Therapies
- Bowel preparation therapy, Eye lubrication
Systane Ultra Versus Maxidex Versus Saline
- Conditions
- Interventions
- First Posted Date
- 2013-01-25
- Last Posted Date
- 2013-01-25
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 36
- Registration Number
- NCT01775540
- Locations
- 🇺🇸
Mount Sinai School of Medicine, New York, New York, United States
A Comparison of 5 Low Volume Bowel Preparations
- Conditions
- Interventions
- First Posted Date
- 2012-11-01
- Last Posted Date
- 2017-03-24
- Lead Sponsor
- Gastroenterology Services, Ltd.
- Target Recruit Count
- 1079
- Registration Number
- NCT01719653
- Locations
- 🇺🇸
Gastroenterology Services, Downers Grove, Illinois, United States
MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery
- Conditions
- Interventions
- First Posted Date
- 2012-09-25
- Last Posted Date
- 2017-02-15
- Lead Sponsor
- Duke University
- Target Recruit Count
- 131
- Registration Number
- NCT01691742
- Locations
- 🇺🇸
Duke University, Department of Urogynecology, Durham, North Carolina, United States
Improving Bowel Preparation for the Colon Capsule
- First Posted Date
- 2012-08-01
- Last Posted Date
- 2015-12-03
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 20
- Registration Number
- NCT01655095
- Locations
- 🇨🇦
Hotel Dieu Hospital, Kingston, Ontario, Canada
Sofosbuvir With Peginterferon Alfa 2a and Ribavirin for 12 Weeks in Treatment-Naive Subjects With Chronic Genotype 1, 4, 5, or 6 HCV Infection
- First Posted Date
- 2012-07-17
- Last Posted Date
- 2014-05-08
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 328
- Registration Number
- NCT01641640
- Locations
- 🇺🇸
Peter J. Ruane, MD, Inc., Los Angeles, California, United States
🇺🇸Borland-Groover Clinic Baptist, Jacksonville, Florida, United States
🇺🇸Infectious Disease Specialist of Atlanta, Decatur, Georgia, United States
Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy
- First Posted Date
- 2012-06-04
- Last Posted Date
- 2012-06-04
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 250
- Registration Number
- NCT01610856
- Locations
- 🇨🇦
Forzani & MacPhail Colon Cancer Screening Centre, Calgary, Alberta, Canada
Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.
- Conditions
- Interventions
- First Posted Date
- 2012-03-29
- Last Posted Date
- 2014-10-01
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 52
- Registration Number
- NCT01565889
- Locations
- 🇵🇷
Fundacion de Investigacion de Diego, San Juan, Puerto Rico
Maintenance Treatment for Children With Constipation
- Conditions
- Interventions
- First Posted Date
- 2012-03-29
- Last Posted Date
- 2016-09-28
- Lead Sponsor
- Line Modin
- Target Recruit Count
- 115
- Registration Number
- NCT01566409
- Locations
- 🇩🇰
Line Modin, Kolding, Denmark
PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
- Conditions
- Interventions
- First Posted Date
- 2012-02-10
- Last Posted Date
- 2012-02-10
- Lead Sponsor
- Medical University of Warsaw
- Target Recruit Count
- 240
- Registration Number
- NCT01531140
- Locations
- 🇵🇱
Warsaw Medical University, Warsaw, Poland
🇵🇱Child Health Center, Warsaw, Poland
Short Course, Single-dose PEG 3350 for Colonoscopy Prep in Children
- First Posted Date
- 2012-01-26
- Last Posted Date
- 2016-02-10
- Lead Sponsor
- Walter Reed National Military Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT01518790
- Locations
- 🇺🇸
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Drug Development Updates
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