Polyethylene glycol
- Generic Name
- Polyethylene glycol
- Brand Names
- Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 25322-68-3
- Unique Ingredient Identifier
- 3WJQ0SDW1A
- Background
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...
- Indication
Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.
- Associated Conditions
- Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
- Associated Therapies
- Bowel preparation therapy, Eye lubrication
Efficacy and Safety of Sofosbuvir Plus Ribavirin in Adults With Chronic HCV Infection
- First Posted Date
- 2013-12-27
- Last Posted Date
- 2018-02-20
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 687
- Registration Number
- NCT02021643
Preparation Prior to Colonoscopy in Children
- Conditions
- Interventions
- First Posted Date
- 2013-12-11
- Last Posted Date
- 2015-05-19
- Lead Sponsor
- Skane University Hospital
- Target Recruit Count
- 71
- Registration Number
- NCT02009202
- Locations
- 🇸🇪
Malmö University, Malmö, Skåne, Sweden
Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients
- Conditions
- Interventions
- First Posted Date
- 2013-08-28
- Last Posted Date
- 2016-04-28
- Lead Sponsor
- Kyungpook National University Hospital
- Target Recruit Count
- 114
- Registration Number
- NCT01929668
- Locations
- 🇰🇷
Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)
- Conditions
- Interventions
- Locations
- 🇺🇸
New York Methodist Hospital, Brooklyn, New York, United States
Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection
- First Posted Date
- 2013-06-26
- Last Posted Date
- 2014-06-17
- Lead Sponsor
- Ospedale Santa Maria delle Croci
- Target Recruit Count
- 116
- Registration Number
- NCT01887158
- Locations
- 🇮🇹
Ospedale S.Maria delle Croci, Ravenna, RA, Italy
🇮🇹Alessandro Mussetto, Ravenna, RA, Italy
Polyethylene Glycol for Childhood Constipation
- First Posted Date
- 2013-06-12
- Last Posted Date
- 2013-11-03
- Lead Sponsor
- Medical University of Warsaw
- Target Recruit Count
- 84
- Registration Number
- NCT01875744
- Locations
- 🇵🇱
Dpt of Pediatrics The Medical University of Warsaw, Warsaw, Poland
Efficacy and Safety Study of Sodium Phosphate Tablets vs PEG for Bowel Cleansing
- Conditions
- Interventions
- First Posted Date
- 2013-04-25
- Last Posted Date
- 2014-03-24
- Lead Sponsor
- Laboratoires Mayoly Spindler
- Target Recruit Count
- 461
- Registration Number
- NCT01840553
- Locations
- 🇫🇷
Hôpital Avicenne, Bobigny, France
🇫🇷Hopital Edouard Herriot, Lyon, France
🇪🇸Hospital 12 de Octubre, Madrid, Spain
Sofosbuvir (GS-7977) in Combination With PEG and Ribavirin for 12 Weeks in Treatment Experienced Subjects With Chronic HCV Infection Genotype 2 or 3
- First Posted Date
- 2013-03-11
- Last Posted Date
- 2014-09-12
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 47
- Registration Number
- NCT01808248
- Locations
- 🇺🇸
Alamo Medical Research, San Antonio, Texas, United States
Trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2013-02-22
- Last Posted Date
- 2013-02-22
- Lead Sponsor
- PVS Memorial Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT01797770
- Locations
- 🇮🇳
PVS Memorial Hospital, Kochi, Kerala, India
A Randomized Prospective Trial Comparing Polyethylene Glycol and Sodium Picosulphate With Magnesium Citrate
- Conditions
- Interventions
- First Posted Date
- 2013-01-29
- Last Posted Date
- 2013-01-31
- Lead Sponsor
- Korea University Anam Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT01778192
- Locations
- 🇰🇷
Division of Gastroenterology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea, Republic of
Drug Development Updates
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