Diazepam

Generic Name
Diazepam
Brand Names
Diastat, Valium, Valtoco 5 Mg Dose Kit
Drug Type
Small Molecule
Chemical Formula
C16H13ClN2O
CAS Number
439-14-5
Unique Ingredient Identifier
Q3JTX2Q7TU
Background

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an an...

Indication

In general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression.
...

Associated Conditions
Acute Agitation, Alcohol Withdrawal Delirium, Alcohol Withdrawal Hallucinosis, Anxiety, Anxiety Disorders, Apprehension, Refractory Epilepsy, Skeletal Muscle Spasms, Status Epilepticus, Stress (Psychology), Tension, Tremor, Convulsive disorders, Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure
Associated Therapies
Sedation, Perioperative management therapy

Nonopioid Analgesia After Rotator Cuff Repair

First Posted Date
2019-01-28
Last Posted Date
2024-04-02
Lead Sponsor
Henry Ford Health System
Target Recruit Count
70
Registration Number
NCT03818919
Locations
🇺🇸

Health Ford Health System, Detroit, Michigan, United States

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-08-31
Last Posted Date
2018-08-31
Lead Sponsor
Avanti Anesthesia
Target Recruit Count
651
Registration Number
NCT03653520
Locations
🇺🇸

Memorial Hermann Kirby Glen Surgery Center, Houston, Texas, United States

Combined Intravenous Diazepam, Local Periprostatic Nerve Block for Prostate Biopsy

First Posted Date
2016-10-18
Last Posted Date
2017-01-23
Lead Sponsor
Assiut University
Target Recruit Count
336
Registration Number
NCT02935972
Locations
🇪🇬

Assiut university hospital, Assiut, Egypt

Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome

First Posted Date
2016-09-16
Last Posted Date
2020-06-11
Lead Sponsor
Mayo Clinic
Target Recruit Count
3
Registration Number
NCT02904265
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing IUD

First Posted Date
2016-06-15
Last Posted Date
2023-08-04
Lead Sponsor
TriHealth Inc.
Target Recruit Count
61
Registration Number
NCT02799641
Locations
🇺🇸

Bethesda North Hospital, Cincinnati, Ohio, United States

Repeat-Dose Pharmacokinetics Study of NRL-1 in Epilepsy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-03-31
Last Posted Date
2021-10-05
Lead Sponsor
Neurelis, Inc.
Target Recruit Count
57
Registration Number
NCT02724423
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Le Bonheur Children's Hospita, Memphis, Tennessee, United States

🇺🇸

University of Virginia, Charlottesville, Virginia, United States

and more 1 locations

Repeat Dose Safety Study of NRL-1 in Epilepsy Subjects

Phase 3
Completed
Conditions
Interventions
First Posted Date
2016-03-28
Last Posted Date
2022-01-31
Lead Sponsor
Neurelis, Inc.
Target Recruit Count
175
Registration Number
NCT02721069
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

🇺🇸

Clinical Trials, Inc., Little Rock, Arkansas, United States

🇺🇸

New York University Comprehensive Epilepsy Center, New York, New York, United States

and more 2 locations

Liposomal Bupivacaine in Implant Based Breast Reconstruction

First Posted Date
2016-01-20
Last Posted Date
2021-01-12
Lead Sponsor
Loma Linda University
Target Recruit Count
24
Registration Number
NCT02659501
Locations
🇺🇸

Loma Linda University Health System, Loma Linda, California, United States

Diazepam Use With Standard Management for Acute Low Back Pain

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-01-05
Last Posted Date
2018-08-01
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
114
Registration Number
NCT02646124
Locations
🇺🇸

Montefiore Medical Center, Bronx, New York, United States

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