Liraglutide

Generic Name
Liraglutide
Brand Names
Saxenda, Victoza, Xultophy
Drug Type
Biotech
Chemical Formula
-
CAS Number
204656-20-2
Unique Ingredient Identifier
839I73S42A
Background

Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist. Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining...

Indication

Saxenda, a formulation of liraglutide intended for weight loss, is indicated as an adjunct to diet and exercise for chronic weight management in adult patients who are obese (BMI≥30 kg/m), or who are overweight (BMI≥27 kg/m) and have at least one weight-related comorbidity. It is also indicated for chronic weight management in pediatric patients ≥12 years ol...

Associated Conditions
Major Adverse Cardiovascular Events, Type 2 Diabetes Mellitus
Associated Therapies
Chronic Weight Management therapy

To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1c

First Posted Date
2006-02-22
Last Posted Date
2017-03-07
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
746
Registration Number
NCT00294723
Locations
🇵🇷

Novo Nordisk Investigational Site, Rio Piedras, Puerto Rico

Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes

Phase 2
Completed
Conditions
First Posted Date
2005-09-12
Last Posted Date
2017-01-25
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
226
Registration Number
NCT00154414
Locations
🇯🇵

Novo Nordisk Investigational Site, Tokyo, Japan

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Phase 2
Completed
Conditions
First Posted Date
2005-09-12
Last Posted Date
2017-01-25
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
177
Registration Number
NCT00154401
Locations
🇸🇰

Novo Nordisk Investigational Site, Zilina, Slovakia

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