Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
-

Study to Evaluate the Effect of Ha44 Gel on the Electrocardiogram in Healthy Volunteers

First Posted Date
2012-01-26
Last Posted Date
2021-07-09
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
57
Registration Number
NCT01518699
Locations
🇺🇸

Spaulding Clinical, West Bend, Wisconsin, United States

Effect of Liraglutide on Heart Frequency in Healthy Volunteers

First Posted Date
2012-01-24
Last Posted Date
2017-01-25
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
64
Registration Number
NCT01516255
Locations
🇺🇸

Novo Nordisk Investigational Site, Fargo, North Dakota, United States

A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers

First Posted Date
2012-01-24
Last Posted Date
2021-04-12
Lead Sponsor
XenoPort, Inc.
Target Recruit Count
52
Registration Number
NCT01516372
Locations
🇺🇸

GSK Investigational Site, Austin, Texas, United States

A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers

First Posted Date
2012-01-23
Last Posted Date
2012-05-09
Lead Sponsor
Achaogen, Inc.
Target Recruit Count
64
Registration Number
NCT01514929
Locations
🇺🇸

Investigational Site, West Bend, Wisconsin, United States

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

First Posted Date
2012-01-18
Last Posted Date
2014-11-25
Lead Sponsor
Knopp Biosciences
Target Recruit Count
68
Registration Number
NCT01511029
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects

First Posted Date
2011-12-07
Last Posted Date
2014-10-10
Lead Sponsor
FORUM Pharmaceuticals Inc
Target Recruit Count
60
Registration Number
NCT01487135

A Study on the Effects of LY2409021 on the Electrical Impulses of the Heart

First Posted Date
2011-10-26
Last Posted Date
2019-01-07
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
67
Registration Number
NCT01460368
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Dallas, Texas, United States

2-Site Safety Study of Besivance Versus Vigamox Prophylactically in Routine Cataract Surgery

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-10-19
Last Posted Date
2011-10-19
Lead Sponsor
Ophthalmology Consultants, Ltd.
Target Recruit Count
60
Registration Number
NCT01455233
Locations
🇺🇸

Ophthalmology Associates, St. Louis, Missouri, United States

🇺🇸

Ophthalmology Consultants, Ltd, St. Louis, Missouri, United States

To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects

First Posted Date
2011-10-10
Last Posted Date
2017-11-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
60
Registration Number
NCT01449188
Locations
🇺🇸

GSK Investigational Site, Austin, Texas, United States

Trial to Evaluate the Effects of OPC-34712 on QT/QTc in Subjects With Schizophrenia or Schizoaffective Disorder

First Posted Date
2011-08-26
Last Posted Date
2015-10-29
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
218
Registration Number
NCT01423916
Locations
🇺🇸

Otsuka Investigational Site, Austin, Texas, United States

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