Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
-

A Randomized, Multiple Dose, Double Blind, 5-way Crossover Study of the Electrocardiographic (ECG) Effects of Bilastine

First Posted Date
2007-01-09
Last Posted Date
2012-04-05
Lead Sponsor
Faes Farma, S.A.
Target Recruit Count
30
Registration Number
NCT00419783
Locations
🇺🇸

MDS Pharma Services, Phoenix, Arizona, United States

Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2006-12-20
Last Posted Date
2013-07-17
Lead Sponsor
Walter Reed Army Medical Center
Target Recruit Count
40
Registration Number
NCT00414011
Locations
🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Therapeutic Variables in Cataract Surgery

Phase 4
Completed
Conditions
First Posted Date
2006-12-04
Last Posted Date
2007-08-21
Lead Sponsor
Innovative Medical
Registration Number
NCT00407017
Locations
🇺🇸

The Center for Excellence in Eye Care, Miami, Florida, United States

Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells

First Posted Date
2006-11-10
Last Posted Date
2015-06-29
Lead Sponsor
University of Cologne
Target Recruit Count
66
Registration Number
NCT00398411
Locations
🇩🇪

Klinikum der Universität zu Köln, Köln, Germany

Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis

First Posted Date
2006-11-06
Last Posted Date
2018-11-08
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
70
Registration Number
NCT00396084
Locations
🇺🇸

San Francisco General Hospital - Pulmonary and Critical Care Medicine, San Francisco, California, United States

🇧🇷

Universidade Federal do Espirito Santo - Duke Hubert-Yeargan Center, Vitória, Espírito Santo, Brazil

A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women

Phase 1
Completed
Conditions
First Posted Date
2006-08-04
Last Posted Date
2022-04-04
Lead Sponsor
AMAG Pharmaceuticals, Inc.
Target Recruit Count
174
Registration Number
NCT00360425

Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora

Phase 4
Completed
Conditions
Interventions
First Posted Date
2006-04-10
Last Posted Date
2012-11-02
Lead Sponsor
Alcon Research
Target Recruit Count
137
Registration Number
NCT00312338
Locations
🇺🇸

Multiple Locations, Fort Worth, Texas, United States

Pharmacokinetic Interaction Study in Indonesian Tuberculosis Patients Indonesia

Phase 2
Completed
Conditions
First Posted Date
2006-03-23
Last Posted Date
2020-11-12
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
23
Registration Number
NCT00306319
Locations
🇮🇩

Rumah Sakit Hasan Sadikin (RSHS), Bandung, Indonesia

A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)

First Posted Date
2005-11-16
Last Posted Date
2009-11-11
Lead Sponsor
Pfizer
Target Recruit Count
398
Registration Number
NCT00254566
Locations
🇹🇭

Pfizer Investigational Site, Khon Kaen, Thailand

Evaluation of Possible Effects on the QT/ QTc Interval of Rupatadine in Healthy Volunteers

First Posted Date
2005-09-20
Last Posted Date
2005-12-15
Lead Sponsor
J. Uriach and Company
Target Recruit Count
160
Registration Number
NCT00199225
Locations
🇪🇸

Centre de Investigació de Medicaments-Intitut de Recerca-Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

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