Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
-

Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial

First Posted Date
2019-05-08
Last Posted Date
2024-05-29
Lead Sponsor
Medecins Sans Frontieres, Netherlands
Target Recruit Count
137
Registration Number
NCT03942354
Locations
๐Ÿ‡ง๐Ÿ‡พ

Republican Scientific and Practical Centre for Pulmonology and Tuberculosis hospital, Minsk, Belarus

๐Ÿ‡บ๐Ÿ‡ฟ

Sh Alimov Republican Specialised Scientific-Practical Medical Centre for Phthysiology and Pulmonology Hospital, Tashkent, Uzbekistan

๐Ÿ‡ฟ๐Ÿ‡ฆ

Helen Jospeh Hospital, Johannesburg, South Africa

and more 3 locations

This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study)

First Posted Date
2019-05-01
Last Posted Date
2024-03-12
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
47
Registration Number
NCT03934203
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

The Physiological Effects of Human Ether-a-go-go-Related Gene (hERG)Blockade on Metabolism

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2019-03-11
Last Posted Date
2022-04-14
Lead Sponsor
Signe Torekov
Target Recruit Count
44
Registration Number
NCT03868657
Locations
๐Ÿ‡ฉ๐Ÿ‡ฐ

University of Copenhagen, Department of Biomedical Sciences, Copenhagen, Denmark

Multiple Ascending Dose Phase I Study in Order to Define Lanifibranor (IVA337) Supra-thjerapeutic Dose

First Posted Date
2019-03-07
Last Posted Date
2019-11-01
Lead Sponsor
Inventiva Pharma
Target Recruit Count
36
Registration Number
NCT03866369
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Parexel International GmbH, Berlin, Germany

A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function

First Posted Date
2019-02-06
Last Posted Date
2019-10-31
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
44
Registration Number
NCT03832452
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

QPS Netherlands B.V., Groningen, Netherlands

Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib

First Posted Date
2019-01-30
Last Posted Date
2019-01-30
Lead Sponsor
Samsung Medical Center
Target Recruit Count
28
Registration Number
NCT03822520
Locations
๐Ÿ‡ฐ๐Ÿ‡ท

Samsung Medical Center, Seoul, Korea, Republic of

Effects of Tucatinib on Cardiac Repolarization in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-12-17
Last Posted Date
2019-04-12
Lead Sponsor
Seagen Inc.
Target Recruit Count
55
Registration Number
NCT03777761
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Covance Clinical Research Unit - Dallas, Dallas, Texas, United States

A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function

First Posted Date
2018-09-05
Last Posted Date
2018-11-20
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
36
Registration Number
NCT03657446
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

QPS Netherlands B.V., Groningen, Netherlands

A Study to Evaluate the PF-06700841 Effect on QTc Interval in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-09-04
Last Posted Date
2019-02-27
Lead Sponsor
Pfizer
Target Recruit Count
33
Registration Number
NCT03656952
Locations
๐Ÿ‡ง๐Ÿ‡ช

Pfizer Clinical Research Unit, Brussels, Belgium

Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects

First Posted Date
2018-08-03
Last Posted Date
2020-03-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
72
Registration Number
NCT03613649
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Vince and Associates Clinical Research, Overland Park, Kansas, United States

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