MedPath

Acamprosate

Generic Name
Acamprosate
Brand Names
Campral
Drug Type
Small Molecule
Chemical Formula
C5H11NO4S
CAS Number
77337-76-9
Unique Ingredient Identifier
N4K14YGM3J

Overview

Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). Acamprosate is the first medication specifically formulated for the maintenance of alcohol abstinence in ethanol-dependent patients after alcohol detoxification, unlike naltrexone and disulfiram. It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.

Background

Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). Acamprosate is the first medication specifically formulated for the maintenance of alcohol abstinence in ethanol-dependent patients after alcohol detoxification, unlike naltrexone and disulfiram. It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.

Indication

Acamprosate is indicated for the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation. It is also indicated for the maintenance of alcohol abstinence in patients who have undergone alcohol detoxification. This drug should be used with a psychosocial support program providing adequate support.

Associated Conditions

  • Alcohol Abstinence
  • Alcohol Dependency

FDA Approved Products

Acamprosate Calcium
Manufacturer:Major Pharmaceuticals
Route:ORAL
Strength:333 mg in 1 1
Approved: 2022/01/31
NDC:0904-7213
acamprosate calcium
Manufacturer:Zydus Pharmaceuticals (USA) Inc.
Route:ORAL
Strength:333 mg in 1 1
Approved: 2023/11/06
NDC:68382-569
Acamprosate Calcium
Manufacturer:American Health Packaging
Route:ORAL
Strength:333 mg in 1 1
Approved: 2023/09/28
NDC:60687-121
acamprosate calcium
Manufacturer:Zydus Lifesciences Limited
Route:ORAL
Strength:333 mg in 1 1
Approved: 2023/11/06
NDC:70771-1057
Campral
Manufacturer:Carilion Materials Management
Route:ORAL
Strength:333 mg in 1 1
Approved: 2012/01/31
NDC:68151-4760

Singapore Approved Products

No Singapore products found for this drug

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