Acamprosate

Generic Name
Acamprosate
Brand Names
Campral
Drug Type
Small Molecule
Chemical Formula
C5H11NO4S
CAS Number
77337-76-9
Unique Ingredient Identifier
N4K14YGM3J
Background

Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending.
...

Indication

Acamprosate is indicated for the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation. It is also indicated for the maintenance of alcohol abstinence in patients who have undergone alcohol detoxification. This drug should be used with a psychosocial support program providing adequate support.

Associated Conditions
Alcohol Abstinence, Alcohol Dependency
Associated Therapies
-

Acamprosate in the Treatment of Binge-Eating Disorder

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-08-06
Last Posted Date
2011-06-22
Lead Sponsor
Lindner Center of HOPE
Target Recruit Count
40
Registration Number
NCT00511940
Locations
🇺🇸

Lindner Center of HOPE, Mason, Ohio, United States

Acamprosate vs. Placebo in Bipolar Alcoholics

First Posted Date
2007-04-27
Last Posted Date
2018-12-14
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
33
Registration Number
NCT00466661
Locations
🇺🇸

Institute of Psychiatry, Medical University of South Carolina, Charleston, South Carolina, United States

Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism

First Posted Date
2007-04-20
Last Posted Date
2020-03-31
Lead Sponsor
Yale University
Target Recruit Count
23
Registration Number
NCT00463346
Locations
🇺🇸

VA Connecticut Healthcare System, West Haven, Connecticut, United States

Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism

First Posted Date
2007-03-27
Last Posted Date
2012-07-09
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
23
Registration Number
NCT00452543
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Comparative Trial Of Disulfiram, Naltrexone And Acamprosate In The Treatment Of Alcohol Dependence

Phase 4
Completed
Conditions
First Posted Date
2007-02-15
Last Posted Date
2007-02-16
Lead Sponsor
Finnish Institute for Health and Welfare
Target Recruit Count
243
Registration Number
NCT00435435
Locations
🇫🇮

National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland

Study of Acamprosate in Driving Under the Influence (DUI) Court Participants

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2007-01-23
Last Posted Date
2012-07-27
Lead Sponsor
University of Oklahoma
Target Recruit Count
4
Registration Number
NCT00425711
Locations
🇺🇸

The University of Oklahoma, Tulsa, Tulsa, Oklahoma, United States

Pilot Trial of Acamprosate for the Treatment of Cocaine Dependence

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-10-09
Last Posted Date
2020-07-10
Lead Sponsor
University of Pennsylvania
Target Recruit Count
60
Registration Number
NCT00385268
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Acamprosate Initiated During Alcohol Detoxification

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-08-04
Last Posted Date
2017-01-11
Lead Sponsor
Forest Laboratories
Target Recruit Count
40
Registration Number
NCT00360594
Locations
🇺🇸

Treatment Research Center, Philadelphia, Pennsylvania, United States

Open Label Trial of Acamprosate in Bipolar Alcoholics

Phase 1
Completed
Conditions
First Posted Date
2006-05-26
Last Posted Date
2008-09-19
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
9
Registration Number
NCT00330486
Locations
🇺🇸

Institute of Psychiatry, Medical University of South Carolina, Charleston, South Carolina, United States

Acamprosate in Alcoholics With Comorbid Anxiety or Depression

First Posted Date
2006-05-26
Last Posted Date
2015-04-13
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
90
Registration Number
NCT00330174
Locations
🇺🇸

Columbia University College of Physicians & Surgeons, New York, New York, United States

🇺🇸

Behavioral Health Services of Pickens County, Pickens, South Carolina, United States

🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

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